Ictal MEG in two children with partial seizures

Harumi Yoshinaga, Yoko Ohtsuka, Yoshiaki Watanabe, Miki Inutsuka, Yoshihiro Kitamura, Kazushi Kinugasa, Eiji Oka

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

We report on the successful identification of epileptic foci in two children with partial epilepsy using ictal magnetoencephalography (MEG). Case 1 is a 12-year-old male suffering with simple partial seizures with leftwards nystagmus. Ictal SPECT revealed a hyperperfusion area in the right lateral occipital area, and MRI revealed cortical dysplasia in the same area. Interictal EEG dipoles were concentrated in the right mesial occipital lobe. Both interictal and ictal MEG dipoles were concentrated in the right mesial occipital lobe, which corresponded well with neuroimaging data and his clinical features. Case 2 is a 5-year-old female suffering with simple partial seizures with left-side facial twitching. Interictal EEG dipoles were located in her left motor area, the pre-sylvian fissure, close to the location of the interictal MEG-estimated dipoles. Ictal EEGs showed no remarkable changes associated with her clinical manifestations. However, ictal MEG showed high-voltage slow waves over her left hemisphere, and ictal MEG iso-contour maps revealed a clear dipolar pattern, which suggested that the MEG dipole was located in the area of the sylvian fissure. Ictal SPECT revealed hyperperfusion areas around the left sylvian fissure. Conclusion: Ictal MEG is useful for determining the precise location of epileptic focus in patients with motionless seizures, including children.

Original languageEnglish
Pages (from-to)403-408
Number of pages6
JournalBrain and Development
Volume26
Issue number6
DOIs
Publication statusPublished - Sep 2004

Fingerprint

Magnetoencephalography
Seizures
Stroke
Partial Epilepsy
Electroencephalography
Occipital Lobe
Single-Photon Emission-Computed Tomography
Malformations of Cortical Development
Motor Cortex
Psychological Stress
Neuroimaging

Keywords

  • Dipole
  • EEG
  • Ictal
  • Localization-related epilepsy
  • Magnetoencephalography

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health
  • Neurology

Cite this

Yoshinaga, H., Ohtsuka, Y., Watanabe, Y., Inutsuka, M., Kitamura, Y., Kinugasa, K., & Oka, E. (2004). Ictal MEG in two children with partial seizures. Brain and Development, 26(6), 403-408. https://doi.org/10.1016/j.braindev.2003.11.003

Ictal MEG in two children with partial seizures. / Yoshinaga, Harumi; Ohtsuka, Yoko; Watanabe, Yoshiaki; Inutsuka, Miki; Kitamura, Yoshihiro; Kinugasa, Kazushi; Oka, Eiji.

In: Brain and Development, Vol. 26, No. 6, 09.2004, p. 403-408.

Research output: Contribution to journalArticle

Yoshinaga, H, Ohtsuka, Y, Watanabe, Y, Inutsuka, M, Kitamura, Y, Kinugasa, K & Oka, E 2004, 'Ictal MEG in two children with partial seizures', Brain and Development, vol. 26, no. 6, pp. 403-408. https://doi.org/10.1016/j.braindev.2003.11.003
Yoshinaga H, Ohtsuka Y, Watanabe Y, Inutsuka M, Kitamura Y, Kinugasa K et al. Ictal MEG in two children with partial seizures. Brain and Development. 2004 Sep;26(6):403-408. https://doi.org/10.1016/j.braindev.2003.11.003
Yoshinaga, Harumi ; Ohtsuka, Yoko ; Watanabe, Yoshiaki ; Inutsuka, Miki ; Kitamura, Yoshihiro ; Kinugasa, Kazushi ; Oka, Eiji. / Ictal MEG in two children with partial seizures. In: Brain and Development. 2004 ; Vol. 26, No. 6. pp. 403-408.
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