Abstract
Two new alkaloids, hyrtimomines D (1) and E (2), were isolated from an Okinawan marine sponge Hyrtios sp. The structures of 1 and 2 were elucidated on the basis of spectroscopic analysis. Hyrtimomines D (1) and E (2) are structurally unique bisindole alkaloids possessing the canthin-6-one skeleton with a hydroxyindole and an imidazolium units. Hyrtimomines D (1) and E (2) exhibited antimicrobial activity.
Original language | English |
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Pages (from-to) | 4038-4040 |
Number of pages | 3 |
Journal | Tetrahedron Letters |
Volume | 54 |
Issue number | 31 |
DOIs | |
Publication status | Published - Jul 31 2013 |
Externally published | Yes |
Keywords
- Bisindole alkaloids
- Hyrtimomines D and E
- Hyrtios sp.
- Marine sponge
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry