Hydroxyapatite formation on CaSiO3 ceramics in protein containing system

Kiyoshi Okada, Punnama Siriphannon, Yoshikazu Kameshima, Atsuo Yasumori, Shigeo Hayashi

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

α-CaSiO3 ceramics with a nominal composition of CaO 46.0, SiO2 54.0, and Na2O 0.4 wt% were soaked in two different solutions, simulated body fluid (SBF) and α-minimum essential medium (α-MEM), to study the effect of protein on the formation of hydroxyapatite (HA). The SBF solution contained the same inorganic salts as in the human blood plasma, while the α-MEM solution contained both inorganic salts and various proteins. Both soaking systems were maintained at 36.5°C and a flow rate of about 40 ml/day for various periods of times. A complete coating of HA formed on the surface of the α-CaSiO3 ceramics in both solutions, but with different formation behavior and microstructure. The HA formed in the α-MEM system had ball-like particle morphology with a smaller particle size than the material formed in the SBF system. Cristobalite and/or unknown silicate phase coprecipitate with the HA in the α-MEM system but not in SBF. The HA layer formed on the ceramic surface achieved a thickness of about 80 and 93 μm after 20 days soaking in SBF and α-MEM solutions, respectively. The presence of protein in the α-MEM solution was considered to effect the microstructure of HA and possibly enhanced HA precipitation on the α-CaSiO3 ceramic.

Original languageEnglish
Pages (from-to)1551-1554
Number of pages4
JournalKey Engineering Materials
Issue number213 PART 3
Publication statusPublished - 2001
Externally publishedYes

Fingerprint

Durapatite
Hydroxyapatite
Body fluids
Proteins
Salts
Silicates
Microstructure
Silicon Dioxide
Blood
Particle size
Flow rate
Plasmas
Coatings
Chemical analysis

Keywords

  • α-casio ceramics
  • Bioactive materials
  • Hydroxyapatite
  • Protein

ASJC Scopus subject areas

  • Ceramics and Composites
  • Chemical Engineering (miscellaneous)

Cite this

Okada, K., Siriphannon, P., Kameshima, Y., Yasumori, A., & Hayashi, S. (2001). Hydroxyapatite formation on CaSiO3 ceramics in protein containing system. Key Engineering Materials, (213 PART 3), 1551-1554.

Hydroxyapatite formation on CaSiO3 ceramics in protein containing system. / Okada, Kiyoshi; Siriphannon, Punnama; Kameshima, Yoshikazu; Yasumori, Atsuo; Hayashi, Shigeo.

In: Key Engineering Materials, No. 213 PART 3, 2001, p. 1551-1554.

Research output: Contribution to journalArticle

Okada, K, Siriphannon, P, Kameshima, Y, Yasumori, A & Hayashi, S 2001, 'Hydroxyapatite formation on CaSiO3 ceramics in protein containing system', Key Engineering Materials, no. 213 PART 3, pp. 1551-1554.
Okada K, Siriphannon P, Kameshima Y, Yasumori A, Hayashi S. Hydroxyapatite formation on CaSiO3 ceramics in protein containing system. Key Engineering Materials. 2001;(213 PART 3):1551-1554.
Okada, Kiyoshi ; Siriphannon, Punnama ; Kameshima, Yoshikazu ; Yasumori, Atsuo ; Hayashi, Shigeo. / Hydroxyapatite formation on CaSiO3 ceramics in protein containing system. In: Key Engineering Materials. 2001 ; No. 213 PART 3. pp. 1551-1554.
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