Abstract
Hydrophobic effects on multivalent-salt-induced self-condensation of a single polyelectrolyte chain such as DNA are investigated through a multiscale coarse-grained simulation based on density functional theory. We show that the water-mediated hydrophobic effect that was enhanced by hydration of multivalent salts plays an essential role in self-condensation of DNA. The self-condensation is interpreted as an entropy-driven compaction due to the hydration entropy gain.
| Original language | English |
|---|---|
| Article number | 161103 |
| Journal | The Journal of Chemical Physics |
| Volume | 131 |
| Issue number | 16 |
| DOIs | |
| Publication status | Published - 2009 |
| Externally published | Yes |
Fingerprint
ASJC Scopus subject areas
- Physics and Astronomy(all)
- Physical and Theoretical Chemistry
- Medicine(all)
Cite this
Hydrophobic effects on multivalent-salt-induced self-condensation of DNA. / Sumi, Tomonari; Suzuki, Chiaki; Sekino, Hideo.
In: The Journal of Chemical Physics, Vol. 131, No. 16, 161103, 2009.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Hydrophobic effects on multivalent-salt-induced self-condensation of DNA
AU - Sumi, Tomonari
AU - Suzuki, Chiaki
AU - Sekino, Hideo
PY - 2009
Y1 - 2009
N2 - Hydrophobic effects on multivalent-salt-induced self-condensation of a single polyelectrolyte chain such as DNA are investigated through a multiscale coarse-grained simulation based on density functional theory. We show that the water-mediated hydrophobic effect that was enhanced by hydration of multivalent salts plays an essential role in self-condensation of DNA. The self-condensation is interpreted as an entropy-driven compaction due to the hydration entropy gain.
AB - Hydrophobic effects on multivalent-salt-induced self-condensation of a single polyelectrolyte chain such as DNA are investigated through a multiscale coarse-grained simulation based on density functional theory. We show that the water-mediated hydrophobic effect that was enhanced by hydration of multivalent salts plays an essential role in self-condensation of DNA. The self-condensation is interpreted as an entropy-driven compaction due to the hydration entropy gain.
UR - http://www.scopus.com/inward/record.url?scp=72049117139&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=72049117139&partnerID=8YFLogxK
U2 - 10.1063/1.3256982
DO - 10.1063/1.3256982
M3 - Article
C2 - 19894915
AN - SCOPUS:72049117139
VL - 131
JO - Journal of Chemical Physics
JF - Journal of Chemical Physics
SN - 0021-9606
IS - 16
M1 - 161103
ER -