Hydrophobic effects on multivalent-salt-induced self-condensation of DNA

Tomonari Sumi, Chiaki Suzuki, Hideo Sekino

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Hydrophobic effects on multivalent-salt-induced self-condensation of a single polyelectrolyte chain such as DNA are investigated through a multiscale coarse-grained simulation based on density functional theory. We show that the water-mediated hydrophobic effect that was enhanced by hydration of multivalent salts plays an essential role in self-condensation of DNA. The self-condensation is interpreted as an entropy-driven compaction due to the hydration entropy gain.

Original languageEnglish
Article number161103
JournalJournal of Chemical Physics
Volume131
Issue number16
DOIs
Publication statusPublished - Dec 21 2009
Externally publishedYes

ASJC Scopus subject areas

  • Physics and Astronomy(all)
  • Physical and Theoretical Chemistry

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