Hydrogel-based biomimetic environment for in vitro cell and tissue manipulation

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

A biomimetic environment fabricated with synthetic material would be an effective tool for reproducing the tissue-developmental process and even for achieving tissue engineering in vitro. A hydrogel material is one candidate for this tool, because a hydrogel normally shows harmless properties in regard to cells and tissue, and it can be tuned chemically and physically to obtain the desired form. Accordingly, fibrin gel was utilized to reproduce the 3D cellular orientations found in muscle tissue, fabricate tendon-like mineralized tissue, and regulate vascular formation. In this context, cell and tissue manipulations within the gel were led by in vitro physical and chemical stimulations. In this chapter, the approach used for manipulating cells and tissues using the designed hydrogel is discussed.

Original languageEnglish
Title of host publicationInterface Oral Health Science 2014: Innovative Research on Biosis-Abiosis Intelligent Interface
PublisherSpringer Japan
Pages161-168
Number of pages8
ISBN (Print)9784431551928, 9784431551256
DOIs
Publication statusPublished - Jan 1 2015

Fingerprint

Biomimetics
Hydrogel
Tissue
Physical Stimulation
Gels
Chemical Stimulation
Tissue Engineering
Fibrin
Tendons
Blood Vessels
Tissue engineering
Muscle
In Vitro Techniques
Muscles

Keywords

  • Biomimetic environment
  • Cell manipulation
  • Hydrogel
  • In vitro tissue engineering

ASJC Scopus subject areas

  • Dentistry(all)
  • Medicine(all)
  • Immunology and Microbiology(all)
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Matsumoto, T. (2015). Hydrogel-based biomimetic environment for in vitro cell and tissue manipulation. In Interface Oral Health Science 2014: Innovative Research on Biosis-Abiosis Intelligent Interface (pp. 161-168). Springer Japan. https://doi.org/10.1007/978-4-431-55192-8_13

Hydrogel-based biomimetic environment for in vitro cell and tissue manipulation. / Matsumoto, Takuya.

Interface Oral Health Science 2014: Innovative Research on Biosis-Abiosis Intelligent Interface. Springer Japan, 2015. p. 161-168.

Research output: Chapter in Book/Report/Conference proceedingChapter

Matsumoto, T 2015, Hydrogel-based biomimetic environment for in vitro cell and tissue manipulation. in Interface Oral Health Science 2014: Innovative Research on Biosis-Abiosis Intelligent Interface. Springer Japan, pp. 161-168. https://doi.org/10.1007/978-4-431-55192-8_13
Matsumoto T. Hydrogel-based biomimetic environment for in vitro cell and tissue manipulation. In Interface Oral Health Science 2014: Innovative Research on Biosis-Abiosis Intelligent Interface. Springer Japan. 2015. p. 161-168 https://doi.org/10.1007/978-4-431-55192-8_13
Matsumoto, Takuya. / Hydrogel-based biomimetic environment for in vitro cell and tissue manipulation. Interface Oral Health Science 2014: Innovative Research on Biosis-Abiosis Intelligent Interface. Springer Japan, 2015. pp. 161-168
@inbook{8cc7e7db78854f33a7e29ad8b0a1a9df,
title = "Hydrogel-based biomimetic environment for in vitro cell and tissue manipulation",
abstract = "A biomimetic environment fabricated with synthetic material would be an effective tool for reproducing the tissue-developmental process and even for achieving tissue engineering in vitro. A hydrogel material is one candidate for this tool, because a hydrogel normally shows harmless properties in regard to cells and tissue, and it can be tuned chemically and physically to obtain the desired form. Accordingly, fibrin gel was utilized to reproduce the 3D cellular orientations found in muscle tissue, fabricate tendon-like mineralized tissue, and regulate vascular formation. In this context, cell and tissue manipulations within the gel were led by in vitro physical and chemical stimulations. In this chapter, the approach used for manipulating cells and tissues using the designed hydrogel is discussed.",
keywords = "Biomimetic environment, Cell manipulation, Hydrogel, In vitro tissue engineering",
author = "Takuya Matsumoto",
year = "2015",
month = "1",
day = "1",
doi = "10.1007/978-4-431-55192-8_13",
language = "English",
isbn = "9784431551928",
pages = "161--168",
booktitle = "Interface Oral Health Science 2014: Innovative Research on Biosis-Abiosis Intelligent Interface",
publisher = "Springer Japan",

}

TY - CHAP

T1 - Hydrogel-based biomimetic environment for in vitro cell and tissue manipulation

AU - Matsumoto, Takuya

PY - 2015/1/1

Y1 - 2015/1/1

N2 - A biomimetic environment fabricated with synthetic material would be an effective tool for reproducing the tissue-developmental process and even for achieving tissue engineering in vitro. A hydrogel material is one candidate for this tool, because a hydrogel normally shows harmless properties in regard to cells and tissue, and it can be tuned chemically and physically to obtain the desired form. Accordingly, fibrin gel was utilized to reproduce the 3D cellular orientations found in muscle tissue, fabricate tendon-like mineralized tissue, and regulate vascular formation. In this context, cell and tissue manipulations within the gel were led by in vitro physical and chemical stimulations. In this chapter, the approach used for manipulating cells and tissues using the designed hydrogel is discussed.

AB - A biomimetic environment fabricated with synthetic material would be an effective tool for reproducing the tissue-developmental process and even for achieving tissue engineering in vitro. A hydrogel material is one candidate for this tool, because a hydrogel normally shows harmless properties in regard to cells and tissue, and it can be tuned chemically and physically to obtain the desired form. Accordingly, fibrin gel was utilized to reproduce the 3D cellular orientations found in muscle tissue, fabricate tendon-like mineralized tissue, and regulate vascular formation. In this context, cell and tissue manipulations within the gel were led by in vitro physical and chemical stimulations. In this chapter, the approach used for manipulating cells and tissues using the designed hydrogel is discussed.

KW - Biomimetic environment

KW - Cell manipulation

KW - Hydrogel

KW - In vitro tissue engineering

UR - http://www.scopus.com/inward/record.url?scp=84956540225&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84956540225&partnerID=8YFLogxK

U2 - 10.1007/978-4-431-55192-8_13

DO - 10.1007/978-4-431-55192-8_13

M3 - Chapter

AN - SCOPUS:84956540225

SN - 9784431551928

SN - 9784431551256

SP - 161

EP - 168

BT - Interface Oral Health Science 2014: Innovative Research on Biosis-Abiosis Intelligent Interface

PB - Springer Japan

ER -