The reaction of internal alkynes (1) with amines (2) in the presence of catalytic amount of Pd(PPh3)4 and benzoic acid in dioxane at 100°C gave the allylic amines (3) in good to excellent yields. The intramolecular reaction of alkynes with tethered amino groups (4) gave 2-vinylpyrrolidines and 2-vinylpiperidines (5) in good to excellent yields.
|Number of pages||11|
|Publication status||Published - Nov 22 2002|
ASJC Scopus subject areas
- Analytical Chemistry
- Organic Chemistry