Human proviral mRNAs down regulated in choriocarcinoma encode a zinc finger protein related to krüppel

Nobuyuki Kato, Kunitada Shimotohno, Donald Vanleeuwen, Maurice Cohen

Research output: Contribution to journalArticle

67 Citations (Scopus)

Abstract

RNA transcripts of the HERV-R (ERV3) human provirus that are abundant in placenta but absent in choriocarcinoma contain nonproviral genomic sequences at their 3′ ends. We report here the isolation of cDNA clones of these genomic sequences. The transcripts encode a Krüppel-related zinc finger protein consisting of a unique leader region and more than 12 28-amino-acid finger motifs.

Original languageEnglish
Pages (from-to)4401-4405
Number of pages5
JournalMolecular and Cellular Biology
Volume10
Issue number8
DOIs
Publication statusPublished - Jan 1 1990

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ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology

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