HPLC retention behavior of poly-aromatic-hydrocarbons on aminopropyl silica gels modified with Cu(II)- and Ni(II)-phthalocyanine derivatives in non-polar eluent

Hiromichi Akizawa, Yuji Kitamura, Minako Yamane, Akimasa Iwado, Junko Oda, Masaki Mifune, Noriko Motohashi, Jun Haginaka, Yutaka Saito

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

A comparative study was conducted to elucidate the mechanism underlying the separation of poly-aromatic-hydrocarbons (PAHs) and related compounds thereof on a column packed with silica gels modified with Ni(II)- or Cu(II)-phthalocyanine derivatives (PCS) (Ni- or Cu-PCSD column) and commercially available PYE® and NPE® columns with a non-polar eluent, such as n-hexane. It has been revealed that the dominant interaction responsible to the separation of PAHs on the Cu-PCSD and the PYE® columns with n-hexane is the π-π interaction; however, in the separation of PAHs having 4 rings such as pyrene on the Ni-PCSD column, participation of π-d interaction was indicated. The predominant role of π-π interaction in the separation of PAHs of less than three rings on the Ni-PCSD column was demonstrated using anthracene. All the columns possessed planar recognition ability and were estimated to be potentially useful in the separation and the analysis of PAHs.

Original languageEnglish
Pages (from-to)41-46
Number of pages6
JournalChemical and Pharmaceutical Bulletin
Volume52
Issue number1
DOIs
Publication statusPublished - Jan 1 2004

Keywords

  • Cu complex
  • HPLC
  • Ni complex
  • Non-polar eluent
  • Phthalocyanine
  • π-π interaction

ASJC Scopus subject areas

  • Chemistry(all)
  • Drug Discovery

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