Host and viral RNA-binding proteins involved in membrane targeting, replication and intercellular movement of plant RNA virus genomes

Kiwamu Hyoudou, Masanori Kaido, Tetsuro Okuno

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Many plant viruses have positive-strand RNA [(+)RNA] as their genome. Therefore, it is not surprising that RNA-binding proteins (RBPs) play important roles during (+)RNA virus infection in host plants. Increasing evidence demonstrates that viral and host RBPs play critical roles in multiple steps of the viral life cycle, including translation and replication of viral genomic RNAs, and their intra- and intercellular movement. Although studies focusing on the RNA-binding activities of viral and host proteins, and their associations with membrane targeting, and intercellular movement of viral genomes have been limited to a few viruses, these studies have provided important insights into the molecular mechanisms underlying the replication and movement of viral genomic RNAs. In this review, we briefly overview the currently defined roles of viral and host RBPs whose RNA-binding activity have been confirmed experimentally in association with their membrane targeting, and intercellular movement of plant RNA virus genomes.

Original languageEnglish
Article number321
JournalFrontiers in Plant Science
Volume5
Issue numberJUL
DOIs
Publication statusPublished - Jul 7 2014
Externally publishedYes

Fingerprint

RNA-binding proteins
viral proteins
RNA
genome
genomics
plant viruses
virus replication
translation (genetics)
RNA viruses
life cycle (organisms)
host plants
viruses
infection
proteins

Keywords

  • Cell-to-cell movement
  • Cellular membrane
  • RNA replication
  • RNA virus
  • RNA-binding protein

ASJC Scopus subject areas

  • Plant Science

Cite this

Host and viral RNA-binding proteins involved in membrane targeting, replication and intercellular movement of plant RNA virus genomes. / Hyoudou, Kiwamu; Kaido, Masanori; Okuno, Tetsuro.

In: Frontiers in Plant Science, Vol. 5, No. JUL, 321, 07.07.2014.

Research output: Contribution to journalArticle

@article{fdb9d7f30b5c486c9283e83e86c4868a,
title = "Host and viral RNA-binding proteins involved in membrane targeting, replication and intercellular movement of plant RNA virus genomes",
abstract = "Many plant viruses have positive-strand RNA [(+)RNA] as their genome. Therefore, it is not surprising that RNA-binding proteins (RBPs) play important roles during (+)RNA virus infection in host plants. Increasing evidence demonstrates that viral and host RBPs play critical roles in multiple steps of the viral life cycle, including translation and replication of viral genomic RNAs, and their intra- and intercellular movement. Although studies focusing on the RNA-binding activities of viral and host proteins, and their associations with membrane targeting, and intercellular movement of viral genomes have been limited to a few viruses, these studies have provided important insights into the molecular mechanisms underlying the replication and movement of viral genomic RNAs. In this review, we briefly overview the currently defined roles of viral and host RBPs whose RNA-binding activity have been confirmed experimentally in association with their membrane targeting, and intercellular movement of plant RNA virus genomes.",
keywords = "Cell-to-cell movement, Cellular membrane, RNA replication, RNA virus, RNA-binding protein",
author = "Kiwamu Hyoudou and Masanori Kaido and Tetsuro Okuno",
year = "2014",
month = "7",
day = "7",
doi = "10.3389/fpls.2014.00321",
language = "English",
volume = "5",
journal = "Frontiers in Plant Science",
issn = "1664-462X",
publisher = "Frontiers Media S. A.",
number = "JUL",

}

TY - JOUR

T1 - Host and viral RNA-binding proteins involved in membrane targeting, replication and intercellular movement of plant RNA virus genomes

AU - Hyoudou, Kiwamu

AU - Kaido, Masanori

AU - Okuno, Tetsuro

PY - 2014/7/7

Y1 - 2014/7/7

N2 - Many plant viruses have positive-strand RNA [(+)RNA] as their genome. Therefore, it is not surprising that RNA-binding proteins (RBPs) play important roles during (+)RNA virus infection in host plants. Increasing evidence demonstrates that viral and host RBPs play critical roles in multiple steps of the viral life cycle, including translation and replication of viral genomic RNAs, and their intra- and intercellular movement. Although studies focusing on the RNA-binding activities of viral and host proteins, and their associations with membrane targeting, and intercellular movement of viral genomes have been limited to a few viruses, these studies have provided important insights into the molecular mechanisms underlying the replication and movement of viral genomic RNAs. In this review, we briefly overview the currently defined roles of viral and host RBPs whose RNA-binding activity have been confirmed experimentally in association with their membrane targeting, and intercellular movement of plant RNA virus genomes.

AB - Many plant viruses have positive-strand RNA [(+)RNA] as their genome. Therefore, it is not surprising that RNA-binding proteins (RBPs) play important roles during (+)RNA virus infection in host plants. Increasing evidence demonstrates that viral and host RBPs play critical roles in multiple steps of the viral life cycle, including translation and replication of viral genomic RNAs, and their intra- and intercellular movement. Although studies focusing on the RNA-binding activities of viral and host proteins, and their associations with membrane targeting, and intercellular movement of viral genomes have been limited to a few viruses, these studies have provided important insights into the molecular mechanisms underlying the replication and movement of viral genomic RNAs. In this review, we briefly overview the currently defined roles of viral and host RBPs whose RNA-binding activity have been confirmed experimentally in association with their membrane targeting, and intercellular movement of plant RNA virus genomes.

KW - Cell-to-cell movement

KW - Cellular membrane

KW - RNA replication

KW - RNA virus

KW - RNA-binding protein

UR - http://www.scopus.com/inward/record.url?scp=84930324511&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84930324511&partnerID=8YFLogxK

U2 - 10.3389/fpls.2014.00321

DO - 10.3389/fpls.2014.00321

M3 - Article

AN - SCOPUS:84930324511

VL - 5

JO - Frontiers in Plant Science

JF - Frontiers in Plant Science

SN - 1664-462X

IS - JUL

M1 - 321

ER -