Abstract
Many plant viruses have positive-strand RNA [(+)RNA] as their genome. Therefore, it is not surprising that RNA-binding proteins (RBPs) play important roles during (+)RNA virus infection in host plants. Increasing evidence demonstrates that viral and host RBPs play critical roles in multiple steps of the viral life cycle, including translation and replication of viral genomic RNAs, and their intra- and intercellular movement. Although studies focusing on the RNA-binding activities of viral and host proteins, and their associations with membrane targeting, and intercellular movement of viral genomes have been limited to a few viruses, these studies have provided important insights into the molecular mechanisms underlying the replication and movement of viral genomic RNAs. In this review, we briefly overview the currently defined roles of viral and host RBPs whose RNA-binding activity have been confirmed experimentally in association with their membrane targeting, and intercellular movement of plant RNA virus genomes.
| Original language | English |
|---|---|
| Article number | 321 |
| Journal | Frontiers in Plant Science |
| Volume | 5 |
| Issue number | JUL |
| DOIs | |
| Publication status | Published - Jul 7 2014 |
| Externally published | Yes |
Fingerprint
Keywords
- Cell-to-cell movement
- Cellular membrane
- RNA replication
- RNA virus
- RNA-binding protein
ASJC Scopus subject areas
- Plant Science
Cite this
Host and viral RNA-binding proteins involved in membrane targeting, replication and intercellular movement of plant RNA virus genomes. / Hyoudou, Kiwamu; Kaido, Masanori; Okuno, Tetsuro.
In: Frontiers in Plant Science, Vol. 5, No. JUL, 321, 07.07.2014.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Host and viral RNA-binding proteins involved in membrane targeting, replication and intercellular movement of plant RNA virus genomes
AU - Hyoudou, Kiwamu
AU - Kaido, Masanori
AU - Okuno, Tetsuro
PY - 2014/7/7
Y1 - 2014/7/7
N2 - Many plant viruses have positive-strand RNA [(+)RNA] as their genome. Therefore, it is not surprising that RNA-binding proteins (RBPs) play important roles during (+)RNA virus infection in host plants. Increasing evidence demonstrates that viral and host RBPs play critical roles in multiple steps of the viral life cycle, including translation and replication of viral genomic RNAs, and their intra- and intercellular movement. Although studies focusing on the RNA-binding activities of viral and host proteins, and their associations with membrane targeting, and intercellular movement of viral genomes have been limited to a few viruses, these studies have provided important insights into the molecular mechanisms underlying the replication and movement of viral genomic RNAs. In this review, we briefly overview the currently defined roles of viral and host RBPs whose RNA-binding activity have been confirmed experimentally in association with their membrane targeting, and intercellular movement of plant RNA virus genomes.
AB - Many plant viruses have positive-strand RNA [(+)RNA] as their genome. Therefore, it is not surprising that RNA-binding proteins (RBPs) play important roles during (+)RNA virus infection in host plants. Increasing evidence demonstrates that viral and host RBPs play critical roles in multiple steps of the viral life cycle, including translation and replication of viral genomic RNAs, and their intra- and intercellular movement. Although studies focusing on the RNA-binding activities of viral and host proteins, and their associations with membrane targeting, and intercellular movement of viral genomes have been limited to a few viruses, these studies have provided important insights into the molecular mechanisms underlying the replication and movement of viral genomic RNAs. In this review, we briefly overview the currently defined roles of viral and host RBPs whose RNA-binding activity have been confirmed experimentally in association with their membrane targeting, and intercellular movement of plant RNA virus genomes.
KW - Cell-to-cell movement
KW - Cellular membrane
KW - RNA replication
KW - RNA virus
KW - RNA-binding protein
UR - http://www.scopus.com/inward/record.url?scp=84930324511&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84930324511&partnerID=8YFLogxK
U2 - 10.3389/fpls.2014.00321
DO - 10.3389/fpls.2014.00321
M3 - Article
AN - SCOPUS:84930324511
VL - 5
JO - Frontiers in Plant Science
JF - Frontiers in Plant Science
SN - 1664-462X
IS - JUL
M1 - 321
ER -