TY - JOUR
T1 - History of diabetes and risk of suicide and accidental death in Japan
T2 - The Japan Public Health Centre-based Prospective Study, 1990-2012
AU - JPHC Study Group
AU - Yamauchi, T.
AU - Inagaki, M.
AU - Yonemoto, N.
AU - Iwasaki, M.
AU - Akechi, T.
AU - Sawada, N.
AU - Iso, H.
AU - Noda, M.
AU - Tsugane, S.
AU - Tsugane, S.
AU - Sasazuki, S.
AU - Yamaji, T.
AU - Shimazu, T.
AU - Hanaoka, T.
AU - Ogata, J.
AU - Baba, T.
AU - Mannami, S.
AU - Okayama, A.
AU - Kokubo, Y.
AU - Miyakawa, K.
AU - Saito, F.
AU - Koizumi, A.
AU - Sano, Y.
AU - Hashimoto, I.
AU - Ikuta, T.
AU - Tanaba, Y.
AU - Sato, H.
AU - Roppongi, Y.
AU - Takashima, T.
AU - Suzuki, H.
AU - Miyajima, Y.
AU - Suzuki, S.
AU - Nagasawa, N.
AU - Furusugi, Y.
AU - Nagai, N.
AU - Ito, Y.
AU - Komatsu, S.
AU - Minamizono, T.
AU - Sanada, H.
AU - Hatayama, Y.
AU - Kobayashi, F.
AU - Uchino, Y.
AU - Shirai, H.
AU - Kondo, T.
AU - Sasaki, R.
AU - Watanabe, Y.
AU - Miyagawa, Y.
AU - Kobayashi, Y.
AU - Machida, M.
AU - Kobayashi, K.
N1 - Funding Information:
This study was supported by the National Cancer Centre Research and Development Fund ( 23-A-31[toku] and 26-A-2 ; since 2011) and a Grant-in-Aid for Cancer Research from the Ministry of Health, Labour and Welfare of Japan (from 1989 to 2010). Funding was also received in the form of science research grants for comprehensive research on disability health and welfare (H25-seishin-ippan-001) from the Ministry of Health, Labour and Welfare of Japan.
Publisher Copyright:
© 2015 Elsevier Masson SAS.
PY - 2016/6/1
Y1 - 2016/6/1
N2 - Aim: This study looked at whether a history of diabetes mellitus (DM) is associated with a higher risk of externally caused death (by suicide and accident), using data for a large population-based prospective cohort from an Asian population. Methods: Data collected between 1990 and 2012 from the Japan Public Health Centre-based Prospective Study were analyzed, and Poisson regression models were used to calculate adjusted risk ratios (RR) for external causes of death. Results: The population-based cohort comprised 105,408 Japanese residents (49,484 men and 55,924 women; mean age: 51.2 [SD 7.9] years). At baseline, 3250 (6.6%) men and 1648 (3.0%) women had a history of DM. During the follow-up period, 113 external deaths (41 suicides and 72 accidents) were noted among those with a history of DM, with 1304 external deaths (577 suicides and 727 accidents) among those without such a history. A higher risk of external death (men, RR: 1.4, 95% CI: 1.2-1.8; women, RR: 1.6, 95% CI: 1.01-2.4) was observed in those with a history of DM. Also, among those aged 40-49 years (RR: 1.9, 95% CI: 1.3-2.7) and 50-59 years (RR: 1.4, 95% CI: 1.05-1.9) at baseline, the risk of external death was significantly higher in those with a history of DM. Conclusion: Compared with people with no history of DM, those with such a history had a significantly greater risk of externally caused death (particularly accidental deaths) in both genders and in those aged ≤ 59 years at baseline.
AB - Aim: This study looked at whether a history of diabetes mellitus (DM) is associated with a higher risk of externally caused death (by suicide and accident), using data for a large population-based prospective cohort from an Asian population. Methods: Data collected between 1990 and 2012 from the Japan Public Health Centre-based Prospective Study were analyzed, and Poisson regression models were used to calculate adjusted risk ratios (RR) for external causes of death. Results: The population-based cohort comprised 105,408 Japanese residents (49,484 men and 55,924 women; mean age: 51.2 [SD 7.9] years). At baseline, 3250 (6.6%) men and 1648 (3.0%) women had a history of DM. During the follow-up period, 113 external deaths (41 suicides and 72 accidents) were noted among those with a history of DM, with 1304 external deaths (577 suicides and 727 accidents) among those without such a history. A higher risk of external death (men, RR: 1.4, 95% CI: 1.2-1.8; women, RR: 1.6, 95% CI: 1.01-2.4) was observed in those with a history of DM. Also, among those aged 40-49 years (RR: 1.9, 95% CI: 1.3-2.7) and 50-59 years (RR: 1.4, 95% CI: 1.05-1.9) at baseline, the risk of external death was significantly higher in those with a history of DM. Conclusion: Compared with people with no history of DM, those with such a history had a significantly greater risk of externally caused death (particularly accidental deaths) in both genders and in those aged ≤ 59 years at baseline.
KW - Accidents
KW - Asian population
KW - Cohort studies
KW - Diabetes mellitus
KW - Prospective studies
KW - Suicide
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U2 - 10.1016/j.diabet.2015.11.008
DO - 10.1016/j.diabet.2015.11.008
M3 - Article
C2 - 26797661
AN - SCOPUS:84956522535
SN - 1262-3636
VL - 42
SP - 184
EP - 191
JO - Diabetes and Metabolism
JF - Diabetes and Metabolism
IS - 3
ER -
