Histopathology and Clinical Results of Carpal Tunnel Syndrome in Idiopathic Cases and Hemodialysis Patients

Kiyoto Kinugasa, Hiroyuki Hashizume, Keiichiro Nishida, Yukio Shigeyama, Hajime Inoue

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

The results of the histological examinations of specimens of the tenosynovium of the flexor tendon, the epineurium and the transverse carpal ligament from two groups of Japanese patients with carpal tunnel syndrome (idiopathic and hemodialysis) were compared. Amyloid deposits, positively identified as β2-microglobulin, appeared in all patients in the long-term hemodialysis group, but in no patients in the idiopathic group. Although the pathogenesis differed between the two groups, both resulted in nerve compression in the carpal tunnel. Therefore, surgical release is considered beneficial for both groups.

Original languageEnglish
Pages (from-to)63-70
Number of pages8
JournalActa Medica Okayama
Volume51
Issue number2
Publication statusPublished - Apr 1997

Fingerprint

Carpal Tunnel Syndrome
Renal Dialysis
Tunnels
Wrist
Ligaments
Tendons
Amyloid
Deposits
Amyloid Plaques
Peripheral Nerves

Keywords

  • Carpal tunnel syndrome
  • Clinical results
  • Hemodialysis
  • Histopathology
  • Idiopathic

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

Histopathology and Clinical Results of Carpal Tunnel Syndrome in Idiopathic Cases and Hemodialysis Patients. / Kinugasa, Kiyoto; Hashizume, Hiroyuki; Nishida, Keiichiro; Shigeyama, Yukio; Inoue, Hajime.

In: Acta Medica Okayama, Vol. 51, No. 2, 04.1997, p. 63-70.

Research output: Contribution to journalArticle

Kinugasa, Kiyoto ; Hashizume, Hiroyuki ; Nishida, Keiichiro ; Shigeyama, Yukio ; Inoue, Hajime. / Histopathology and Clinical Results of Carpal Tunnel Syndrome in Idiopathic Cases and Hemodialysis Patients. In: Acta Medica Okayama. 1997 ; Vol. 51, No. 2. pp. 63-70.
@article{e47b6bf64ecb434ebb7565e5649c7abb,
title = "Histopathology and Clinical Results of Carpal Tunnel Syndrome in Idiopathic Cases and Hemodialysis Patients",
abstract = "The results of the histological examinations of specimens of the tenosynovium of the flexor tendon, the epineurium and the transverse carpal ligament from two groups of Japanese patients with carpal tunnel syndrome (idiopathic and hemodialysis) were compared. Amyloid deposits, positively identified as β2-microglobulin, appeared in all patients in the long-term hemodialysis group, but in no patients in the idiopathic group. Although the pathogenesis differed between the two groups, both resulted in nerve compression in the carpal tunnel. Therefore, surgical release is considered beneficial for both groups.",
keywords = "Carpal tunnel syndrome, Clinical results, Hemodialysis, Histopathology, Idiopathic",
author = "Kiyoto Kinugasa and Hiroyuki Hashizume and Keiichiro Nishida and Yukio Shigeyama and Hajime Inoue",
year = "1997",
month = "4",
language = "English",
volume = "51",
pages = "63--70",
journal = "Acta Medica Okayama",
issn = "0386-300X",
publisher = "Okayama University",
number = "2",

}

TY - JOUR

T1 - Histopathology and Clinical Results of Carpal Tunnel Syndrome in Idiopathic Cases and Hemodialysis Patients

AU - Kinugasa, Kiyoto

AU - Hashizume, Hiroyuki

AU - Nishida, Keiichiro

AU - Shigeyama, Yukio

AU - Inoue, Hajime

PY - 1997/4

Y1 - 1997/4

N2 - The results of the histological examinations of specimens of the tenosynovium of the flexor tendon, the epineurium and the transverse carpal ligament from two groups of Japanese patients with carpal tunnel syndrome (idiopathic and hemodialysis) were compared. Amyloid deposits, positively identified as β2-microglobulin, appeared in all patients in the long-term hemodialysis group, but in no patients in the idiopathic group. Although the pathogenesis differed between the two groups, both resulted in nerve compression in the carpal tunnel. Therefore, surgical release is considered beneficial for both groups.

AB - The results of the histological examinations of specimens of the tenosynovium of the flexor tendon, the epineurium and the transverse carpal ligament from two groups of Japanese patients with carpal tunnel syndrome (idiopathic and hemodialysis) were compared. Amyloid deposits, positively identified as β2-microglobulin, appeared in all patients in the long-term hemodialysis group, but in no patients in the idiopathic group. Although the pathogenesis differed between the two groups, both resulted in nerve compression in the carpal tunnel. Therefore, surgical release is considered beneficial for both groups.

KW - Carpal tunnel syndrome

KW - Clinical results

KW - Hemodialysis

KW - Histopathology

KW - Idiopathic

UR - http://www.scopus.com/inward/record.url?scp=0031111178&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031111178&partnerID=8YFLogxK

M3 - Article

C2 - 9142342

AN - SCOPUS:0031111178

VL - 51

SP - 63

EP - 70

JO - Acta Medica Okayama

JF - Acta Medica Okayama

SN - 0386-300X

IS - 2

ER -