Histopathological Investigation in Meningioangiomatosis

Katsuzo Kunishio, Yoshihiro Yamamoto, Norio Sunami, Yuji Yamamoto, Toru Satoh, Shoji Asari, Tadashi Yoshino, Yuji Ohtsuki

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

A case of meningioangiomatosis without association with von Recklinghausen’s disease is reported. A 39-year-old man was admitted because of head injury. Computed tomography (CT) scan show-ed right acute epidural hematoma, left intracerebral hematoma, and a mass with calcification in the right parietal region. Craniotomy, evacuation of epidural hematoma, and external decompression were performed. Enhanced CT scan revealed that the mass was slightly enhanced around calcifica-tion. Angiography demonstrated an avascular mass. Cranioplasty and partial removal of the mass were carried out. Microscopically, irregularly-branched thick-walled blood vessels extended into the gray matter from the meningeal surface, and proliferated blood vessels were surrounded by wavy or concentric arrangement of spindle-form cells in association with intervening neural tissue. A diag-nosis of meningioangiomatosis was made. Spindle-form cells were not found to contain S-100 pro-tein. Electron microscopic findings demonstrated that the proliferating cells were composed of spindle-form nuclei rich in heterochromatin and slender cytoplasm containing micro filaments, in association with desmosomal junctions and basal lamina-like structure on occasion. These findings disclosed that spindle-form cells were not derived from Schwann cells but that they may be menin-gothelial cells in origin.

Original languageEnglish
Pages (from-to)240-243
Number of pages4
JournalNeurologia Medico-Chirurgica
Volume27
Issue number3
DOIs
Publication statusPublished - 1987
Externally publishedYes

Fingerprint

Hematoma
Blood Vessels
Tomography
Parietal Lobe
Neurofibromatosis 1
Heterochromatin
Craniotomy
Schwann Cells
Decompression
Craniocerebral Trauma
Basement Membrane
Angiography
Cytoplasm
Electrons
Gray Matter

Keywords

  • computed tomography
  • histogenesis
  • histopathology
  • meningioangiomatosis
  • ultrastructure

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

Cite this

Kunishio, K., Yamamoto, Y., Sunami, N., Yamamoto, Y., Satoh, T., Asari, S., ... Ohtsuki, Y. (1987). Histopathological Investigation in Meningioangiomatosis. Neurologia Medico-Chirurgica, 27(3), 240-243. https://doi.org/10.2176/nmc.27.240

Histopathological Investigation in Meningioangiomatosis. / Kunishio, Katsuzo; Yamamoto, Yoshihiro; Sunami, Norio; Yamamoto, Yuji; Satoh, Toru; Asari, Shoji; Yoshino, Tadashi; Ohtsuki, Yuji.

In: Neurologia Medico-Chirurgica, Vol. 27, No. 3, 1987, p. 240-243.

Research output: Contribution to journalArticle

Kunishio, K, Yamamoto, Y, Sunami, N, Yamamoto, Y, Satoh, T, Asari, S, Yoshino, T & Ohtsuki, Y 1987, 'Histopathological Investigation in Meningioangiomatosis', Neurologia Medico-Chirurgica, vol. 27, no. 3, pp. 240-243. https://doi.org/10.2176/nmc.27.240
Kunishio, Katsuzo ; Yamamoto, Yoshihiro ; Sunami, Norio ; Yamamoto, Yuji ; Satoh, Toru ; Asari, Shoji ; Yoshino, Tadashi ; Ohtsuki, Yuji. / Histopathological Investigation in Meningioangiomatosis. In: Neurologia Medico-Chirurgica. 1987 ; Vol. 27, No. 3. pp. 240-243.
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