Histopathological incidence of facial canal dehiscence in otosclerosis

Shigenobu Nomiya, Sebahattin Cureoglu, Shin Kariya, Norimasa Morita, Rie Nomiya, Kazunori Nishizaki, Michael M. Paparella

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Abstract

The objective of this study was to evaluate the histopathological incidence of facial canal dehiscence in otosclerosis cases compared with non-otosclerotic controls. 133 temporal bones from 84 otosclerosis (35 unilateral otosclerosis, 49 bilateral otosclerosis) cases were compared to 102 age-matched normal temporal bones from 70 subjects (38 unilateral normal cases, 32 bilateral normal cases). Temporal bones were serially sectioned in the horizontal plane at a thickness of 20 μm, and were stained with hematoxylin and eosin. We evaluated the location and the invasion of otosclerosis to the facial canal and incidence of facial canal dehiscence under light microscopy. Facial canal was subdivided into four portions: (1) the geniculate ganglion, (2) the tensor tympani muscle, (3) the oval window, and (4) mastoid. The incidence of facial canal dehiscence in otosclerosis [66 temporal bones (49.6%)] was significantly lower than normal controls [67 control temporal bones (65.7%)] in the oval window area (P = 0.019). Temporal bones with otosclerotic invasion to the thin bone of the canal were significantly less likely to have dehiscence [10 temporal bones (31.3%)] compared to the otosclerotic bones without invasion [56 temporal bones (55.5%)] (P = 0.025). There was no significant difference in the incidence of facial canal dehiscence between temporal bones with and without otosclerosis in the entire segment of facial nerve. Our findings in this study suggest that otosclerotic lesions have the potential to close dehiscence of the facial canal in the oval window area.

Original languageEnglish
Pages (from-to)1267-1271
Number of pages5
JournalEuropean Archives of Oto-Rhino-Laryngology
Volume268
Issue number9
DOIs
Publication statusPublished - Sep 2011

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Keywords

  • Facial canal dehiscence
  • Facial nerve
  • Otosclerosis
  • Temporal bone

ASJC Scopus subject areas

  • Otorhinolaryngology

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