Histopathological examination of newly-developed adhesive silicone denture relining material

Mihoko Tomida; K. Nakano; M. Sato; S. Matsuura; T. Kawakami

doi:10.1186/2047-783x-16-7-328

Histopathological examination of newly-developed adhesive silicone denture relining material

Mihoko Tomida, K. Nakano, M. Sato, S. Matsuura, T. Kawakami

Research output: Contribution to journal › Article › peer-review

Abstract

We aimed to evaluate the subcutaneous tissue reaction to a newly developed adhesive silicone denture relining material, SG, (Neo Dental Chemical Products Co., Ltd. Tokyo, Japan). We embedded the experimental material SG and another existing control material, Roeko Seal (RS), in the dorsal area of 22 male ddY mice. One week and 12 weeks after the embedding, the tissues surrounding the embedded materials were removed and a histopathological examination was performed. The results demonstrate that the basic histopathological aspects are the formation of granulation tissue and the change of the tissue to fibrous capsule over time. The results suggests that the newly-developed SG is safe as compared with the control RS, whose composition is similar.

Original language	English
Pages (from-to)	328-330
Number of pages	3
Journal	European journal of medical research
Volume	16
Issue number	7
DOIs	https://doi.org/10.1186/2047-783x-16-7-328
Publication status	Published - Jul 25 2011

Keywords

Histopathological evaluation
Silicone-containing material
Tissue reaction

ASJC Scopus subject areas

Medicine(all)

Access to Document

10.1186/2047-783x-16-7-328

Fingerprint Dive into the research topics of 'Histopathological examination of newly-developed adhesive silicone denture relining material'. Together they form a unique fingerprint.

Cite this

@article{a4c50c677252402c85482dd19957d232,

title = "Histopathological examination of newly-developed adhesive silicone denture relining material",

abstract = "We aimed to evaluate the subcutaneous tissue reaction to a newly developed adhesive silicone denture relining material, SG, (Neo Dental Chemical Products Co., Ltd. Tokyo, Japan). We embedded the experimental material SG and another existing control material, Roeko Seal (RS), in the dorsal area of 22 male ddY mice. One week and 12 weeks after the embedding, the tissues surrounding the embedded materials were removed and a histopathological examination was performed. The results demonstrate that the basic histopathological aspects are the formation of granulation tissue and the change of the tissue to fibrous capsule over time. The results suggests that the newly-developed SG is safe as compared with the control RS, whose composition is similar.",

keywords = "Histopathological evaluation, Silicone-containing material, Tissue reaction",

author = "Mihoko Tomida and K. Nakano and M. Sato and S. Matsuura and T. Kawakami",

year = "2011",

month = jul,

day = "25",

doi = "10.1186/2047-783x-16-7-328",

language = "English",

volume = "16",

pages = "328--330",

journal = "European Journal of Medical Research",

issn = "0949-2321",

publisher = "BioMed Central",

number = "7",

}

TY - JOUR

T1 - Histopathological examination of newly-developed adhesive silicone denture relining material

AU - Tomida, Mihoko

AU - Nakano, K.

AU - Sato, M.

AU - Matsuura, S.

AU - Kawakami, T.

PY - 2011/7/25

Y1 - 2011/7/25

N2 - We aimed to evaluate the subcutaneous tissue reaction to a newly developed adhesive silicone denture relining material, SG, (Neo Dental Chemical Products Co., Ltd. Tokyo, Japan). We embedded the experimental material SG and another existing control material, Roeko Seal (RS), in the dorsal area of 22 male ddY mice. One week and 12 weeks after the embedding, the tissues surrounding the embedded materials were removed and a histopathological examination was performed. The results demonstrate that the basic histopathological aspects are the formation of granulation tissue and the change of the tissue to fibrous capsule over time. The results suggests that the newly-developed SG is safe as compared with the control RS, whose composition is similar.

AB - We aimed to evaluate the subcutaneous tissue reaction to a newly developed adhesive silicone denture relining material, SG, (Neo Dental Chemical Products Co., Ltd. Tokyo, Japan). We embedded the experimental material SG and another existing control material, Roeko Seal (RS), in the dorsal area of 22 male ddY mice. One week and 12 weeks after the embedding, the tissues surrounding the embedded materials were removed and a histopathological examination was performed. The results demonstrate that the basic histopathological aspects are the formation of granulation tissue and the change of the tissue to fibrous capsule over time. The results suggests that the newly-developed SG is safe as compared with the control RS, whose composition is similar.

KW - Histopathological evaluation

KW - Silicone-containing material

KW - Tissue reaction

UR - http://www.scopus.com/inward/record.url?scp=80051702886&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=80051702886&partnerID=8YFLogxK

U2 - 10.1186/2047-783x-16-7-328

DO - 10.1186/2047-783x-16-7-328

M3 - Article

C2 - 21813374

AN - SCOPUS:80051702886

VL - 16

SP - 328

EP - 330

JO - European Journal of Medical Research

JF - European Journal of Medical Research

SN - 0949-2321

IS - 7

ER -