Abstract
We aimed to evaluate the subcutaneous tissue reaction to a newly developed adhesive silicone denture relining material, SG, (Neo Dental Chemical Products Co., Ltd. Tokyo, Japan). We embedded the experimental material SG and another existing control material, Roeko Seal (RS), in the dorsal area of 22 male ddY mice. One week and 12 weeks after the embedding, the tissues surrounding the embedded materials were removed and a histopathological examination was performed. The results demonstrate that the basic histopathological aspects are the formation of granulation tissue and the change of the tissue to fibrous capsule over time. The results suggests that the newly-developed SG is safe as compared with the control RS, whose composition is similar.
| Original language | English |
|---|---|
| Pages (from-to) | 328-330 |
| Number of pages | 3 |
| Journal | European Journal of Medical Research |
| Volume | 16 |
| Issue number | 7 |
| Publication status | Published - Jul 25 2011 |
| Externally published | Yes |
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Keywords
- Histopathological evaluation
- Silicone-containing material
- Tissue reaction
ASJC Scopus subject areas
- Medicine(all)
Cite this
Histopathological examination of newly-developed adhesive silicone denture relining material. / Tomida, Mihoko; Nakano, Keisuke; Sato, M.; Matsuura, S.; Kawakami, T.
In: European Journal of Medical Research, Vol. 16, No. 7, 25.07.2011, p. 328-330.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Histopathological examination of newly-developed adhesive silicone denture relining material
AU - Tomida, Mihoko
AU - Nakano, Keisuke
AU - Sato, M.
AU - Matsuura, S.
AU - Kawakami, T.
PY - 2011/7/25
Y1 - 2011/7/25
N2 - We aimed to evaluate the subcutaneous tissue reaction to a newly developed adhesive silicone denture relining material, SG, (Neo Dental Chemical Products Co., Ltd. Tokyo, Japan). We embedded the experimental material SG and another existing control material, Roeko Seal (RS), in the dorsal area of 22 male ddY mice. One week and 12 weeks after the embedding, the tissues surrounding the embedded materials were removed and a histopathological examination was performed. The results demonstrate that the basic histopathological aspects are the formation of granulation tissue and the change of the tissue to fibrous capsule over time. The results suggests that the newly-developed SG is safe as compared with the control RS, whose composition is similar.
AB - We aimed to evaluate the subcutaneous tissue reaction to a newly developed adhesive silicone denture relining material, SG, (Neo Dental Chemical Products Co., Ltd. Tokyo, Japan). We embedded the experimental material SG and another existing control material, Roeko Seal (RS), in the dorsal area of 22 male ddY mice. One week and 12 weeks after the embedding, the tissues surrounding the embedded materials were removed and a histopathological examination was performed. The results demonstrate that the basic histopathological aspects are the formation of granulation tissue and the change of the tissue to fibrous capsule over time. The results suggests that the newly-developed SG is safe as compared with the control RS, whose composition is similar.
KW - Histopathological evaluation
KW - Silicone-containing material
KW - Tissue reaction
UR - http://www.scopus.com/inward/record.url?scp=80051702886&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=80051702886&partnerID=8YFLogxK
M3 - Article
VL - 16
SP - 328
EP - 330
JO - European Journal of Medical Research
JF - European Journal of Medical Research
SN - 0949-2321
IS - 7
ER -