Histological features responsible for brownish epithelium in squamous neoplasia of the esophagus by narrow band imaging

Hiromitsu Kanzaki; Ryu Ishihara; Shingo Ishiguro; Kengo Nagai; Fumi Matsui; Takeshi Yamashina; Takashi Ohta; Sachiko Yamamoto; Noboru Hanaoka; Masao Hanafusa; Yoji Takeuchi; Koji Higashino; Noriya Uedo; Hiroyasu Iishi; Yasuhiko Tomita

doi:10.1111/jgh.12059

Histological features responsible for brownish epithelium in squamous neoplasia of the esophagus by narrow band imaging

Hiromitsu Kanzaki, Ryu Ishihara, Shingo Ishiguro, Kengo Nagai, Fumi Matsui, Takeshi Yamashina, Takashi Ohta, Sachiko Yamamoto, Noboru Hanaoka, Masao Hanafusa, Yoji Takeuchi, Koji Higashino, Noriya Uedo, Hiroyasu Iishi, Yasuhiko Tomita

Research output: Contribution to journal › Article

12 Citations (Scopus)

Abstract

Background and Aim: Esophageal squamous neoplasias usually appear brown under narrow band imaging as a result of microvascular proliferation, and brownish color changes in the areas between vessels, referred to as brownish epithelium. However, the reasons for the development of this brownish epithelium and its clinical implications have not been fully investigated. Methods: Patients with superficial esophageal neoplasias treated by endoscopic resection were included in the study. Areas of mucosa with brownish and non-brownish epithelia were evaluated histologically. Results: A total of 68 superficial esophageal neoplasias in 58 patients were included in the analysis. Of the 68 lesions, 32 were classified in the brownish epithelium group, and 36 in the non-brownish epithelium group. Brownish epithelium was significantly associated with a diagnosis of high-grade intraepithelial neoplasia or invasive cancer (P

Original language	English
Pages (from-to)	274-278
Number of pages	5
Journal	Journal of Gastroenterology and Hepatology (Australia)
Volume	28
Issue number	2
DOIs	https://doi.org/10.1111/jgh.12059
Publication status	Published - 2013
Externally published	Yes

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Keywords

Brownish area
Brownish epithelium
Esophageal cancer
Esophageal squamous neoplasia
Narrow band imaging

ASJC Scopus subject areas

Gastroenterology
Hepatology

Cite this

Kanzaki, H., Ishihara, R., Ishiguro, S., Nagai, K., Matsui, F., Yamashina, T., Ohta, T., Yamamoto, S., Hanaoka, N., Hanafusa, M., Takeuchi, Y., Higashino, K., Uedo, N., Iishi, H., & Tomita, Y. (2013). Histological features responsible for brownish epithelium in squamous neoplasia of the esophagus by narrow band imaging. Journal of Gastroenterology and Hepatology (Australia), 28(2), 274-278. https://doi.org/10.1111/jgh.12059

Histological features responsible for brownish epithelium in squamous neoplasia of the esophagus by narrow band imaging. / Kanzaki, Hiromitsu; Ishihara, Ryu; Ishiguro, Shingo; Nagai, Kengo; Matsui, Fumi; Yamashina, Takeshi; Ohta, Takashi; Yamamoto, Sachiko; Hanaoka, Noboru; Hanafusa, Masao; Takeuchi, Yoji; Higashino, Koji; Uedo, Noriya; Iishi, Hiroyasu; Tomita, Yasuhiko.

In: Journal of Gastroenterology and Hepatology (Australia), Vol. 28, No. 2, 2013, p. 274-278.

Research output: Contribution to journal › Article

Kanzaki, H, Ishihara, R, Ishiguro, S, Nagai, K, Matsui, F, Yamashina, T, Ohta, T, Yamamoto, S, Hanaoka, N, Hanafusa, M, Takeuchi, Y, Higashino, K, Uedo, N, Iishi, H & Tomita, Y 2013, 'Histological features responsible for brownish epithelium in squamous neoplasia of the esophagus by narrow band imaging', Journal of Gastroenterology and Hepatology (Australia), vol. 28, no. 2, pp. 274-278. https://doi.org/10.1111/jgh.12059

Kanzaki, Hiromitsu ; Ishihara, Ryu ; Ishiguro, Shingo ; Nagai, Kengo ; Matsui, Fumi ; Yamashina, Takeshi ; Ohta, Takashi ; Yamamoto, Sachiko ; Hanaoka, Noboru ; Hanafusa, Masao ; Takeuchi, Yoji ; Higashino, Koji ; Uedo, Noriya ; Iishi, Hiroyasu ; Tomita, Yasuhiko. / Histological features responsible for brownish epithelium in squamous neoplasia of the esophagus by narrow band imaging. In: Journal of Gastroenterology and Hepatology (Australia). 2013 ; Vol. 28, No. 2. pp. 274-278.

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AU - Ohta, Takashi

AU - Yamamoto, Sachiko

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AU - Hanafusa, Masao

AU - Takeuchi, Yoji

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AU - Uedo, Noriya

AU - Iishi, Hiroyasu

AU - Tomita, Yasuhiko

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10.1111/jgh.12059