Histological determination of the areas enriched in cholinergic terminals and m2 and m3 muscarinic receptors in the mouse central auditory system

Satoko Hamada, Takeshi Houtani, Stefan Trifonov, Masahiko Kase, Masato Maruyama, Jun Ichi Shimizu, Toshio Yamashita, Koichi Tomoda, Tetsuo Sugimoto

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Cholinergic projections to auditory system are vital for coupling arousal with sound processing. Systematic search with in situ hybridization and immunohistochemistry indicated that the ventral nucleus of the medial geniculate body and the nucleus of the brachium of the inferior colliculus constituted cholinergic synaptic sites in the brainstem auditory system, containing a significant number of cholinergic axon terminals and m2 receptor-expressing cell bodies.

Original languageEnglish
Pages (from-to)1393-1399
Number of pages7
JournalAnatomical Record
Volume293
Issue number8
DOIs
Publication statusPublished - Aug 1 2010
Externally publishedYes

Fingerprint

Muscarinic M3 Receptors
Muscarinic M2 Receptors
cholinergic agents
Cholinergic Agents
Geniculate Bodies
receptors
mice
Inferior Colliculi
Presynaptic Terminals
brain stem
Arousal
axons
in situ hybridization
Brain Stem
In Situ Hybridization
immunohistochemistry
Arm
Immunohistochemistry
in situ
sound

Keywords

  • Central auditory system
  • Muscarinic receptors
  • Vesicular acetylcholine transporter

ASJC Scopus subject areas

  • Anatomy
  • Histology
  • Ecology, Evolution, Behavior and Systematics
  • Biotechnology
  • Medicine(all)

Cite this

Histological determination of the areas enriched in cholinergic terminals and m2 and m3 muscarinic receptors in the mouse central auditory system. / Hamada, Satoko; Houtani, Takeshi; Trifonov, Stefan; Kase, Masahiko; Maruyama, Masato; Shimizu, Jun Ichi; Yamashita, Toshio; Tomoda, Koichi; Sugimoto, Tetsuo.

In: Anatomical Record, Vol. 293, No. 8, 01.08.2010, p. 1393-1399.

Research output: Contribution to journalArticle

Hamada, S, Houtani, T, Trifonov, S, Kase, M, Maruyama, M, Shimizu, JI, Yamashita, T, Tomoda, K & Sugimoto, T 2010, 'Histological determination of the areas enriched in cholinergic terminals and m2 and m3 muscarinic receptors in the mouse central auditory system', Anatomical Record, vol. 293, no. 8, pp. 1393-1399. https://doi.org/10.1002/ar.21186
Hamada, Satoko ; Houtani, Takeshi ; Trifonov, Stefan ; Kase, Masahiko ; Maruyama, Masato ; Shimizu, Jun Ichi ; Yamashita, Toshio ; Tomoda, Koichi ; Sugimoto, Tetsuo. / Histological determination of the areas enriched in cholinergic terminals and m2 and m3 muscarinic receptors in the mouse central auditory system. In: Anatomical Record. 2010 ; Vol. 293, No. 8. pp. 1393-1399.
@article{d1f764e7016143678d72c014f7bd3726,
title = "Histological determination of the areas enriched in cholinergic terminals and m2 and m3 muscarinic receptors in the mouse central auditory system",
abstract = "Cholinergic projections to auditory system are vital for coupling arousal with sound processing. Systematic search with in situ hybridization and immunohistochemistry indicated that the ventral nucleus of the medial geniculate body and the nucleus of the brachium of the inferior colliculus constituted cholinergic synaptic sites in the brainstem auditory system, containing a significant number of cholinergic axon terminals and m2 receptor-expressing cell bodies.",
keywords = "Central auditory system, Muscarinic receptors, Vesicular acetylcholine transporter",
author = "Satoko Hamada and Takeshi Houtani and Stefan Trifonov and Masahiko Kase and Masato Maruyama and Shimizu, {Jun Ichi} and Toshio Yamashita and Koichi Tomoda and Tetsuo Sugimoto",
year = "2010",
month = "8",
day = "1",
doi = "10.1002/ar.21186",
language = "English",
volume = "293",
pages = "1393--1399",
journal = "Anatomical Record",
issn = "1932-8486",
publisher = "John Wiley and Sons Inc.",
number = "8",

}

TY - JOUR

T1 - Histological determination of the areas enriched in cholinergic terminals and m2 and m3 muscarinic receptors in the mouse central auditory system

AU - Hamada, Satoko

AU - Houtani, Takeshi

AU - Trifonov, Stefan

AU - Kase, Masahiko

AU - Maruyama, Masato

AU - Shimizu, Jun Ichi

AU - Yamashita, Toshio

AU - Tomoda, Koichi

AU - Sugimoto, Tetsuo

PY - 2010/8/1

Y1 - 2010/8/1

N2 - Cholinergic projections to auditory system are vital for coupling arousal with sound processing. Systematic search with in situ hybridization and immunohistochemistry indicated that the ventral nucleus of the medial geniculate body and the nucleus of the brachium of the inferior colliculus constituted cholinergic synaptic sites in the brainstem auditory system, containing a significant number of cholinergic axon terminals and m2 receptor-expressing cell bodies.

AB - Cholinergic projections to auditory system are vital for coupling arousal with sound processing. Systematic search with in situ hybridization and immunohistochemistry indicated that the ventral nucleus of the medial geniculate body and the nucleus of the brachium of the inferior colliculus constituted cholinergic synaptic sites in the brainstem auditory system, containing a significant number of cholinergic axon terminals and m2 receptor-expressing cell bodies.

KW - Central auditory system

KW - Muscarinic receptors

KW - Vesicular acetylcholine transporter

UR - http://www.scopus.com/inward/record.url?scp=77955640564&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77955640564&partnerID=8YFLogxK

U2 - 10.1002/ar.21186

DO - 10.1002/ar.21186

M3 - Article

C2 - 20665816

AN - SCOPUS:77955640564

VL - 293

SP - 1393

EP - 1399

JO - Anatomical Record

JF - Anatomical Record

SN - 1932-8486

IS - 8

ER -