Highly sensitive chiral shift reagent bearing two zinc porphyrins

Tadashi Ema, Nozomi Ouchi, Tokuhiro Doi, Toshinobu Korenaga, Takashi Sakai

Research output: Contribution to journalArticle

48 Citations (Scopus)

Abstract

(Chemical Equation Presented) A new type of chiral receptor (R,R)- or (S,S)-1b with C2 symmetry was synthesized. An induced-fit type of binding behavior of 1b for diamines was revealed by CD spectroscopy. NMR studies demonstrated that 1b can function as a highly sensitive chiral shift reagent for the determination of the enantiomeric purity of chiral diamines, aziridine, and isoxazoline at the microgram level.

Original languageEnglish
Pages (from-to)3985-3988
Number of pages4
JournalOrganic Letters
Volume7
Issue number18
DOIs
Publication statusPublished - Sep 1 2005

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Bearings (structural)
Diamines
diamines
porphyrins
reagents
zinc
shift
Spectrum Analysis
purity
Nuclear magnetic resonance
Spectroscopy
nuclear magnetic resonance
symmetry
spectroscopy
zinc hematoporphyrin

ASJC Scopus subject areas

  • Molecular Medicine

Cite this

Highly sensitive chiral shift reagent bearing two zinc porphyrins. / Ema, Tadashi; Ouchi, Nozomi; Doi, Tokuhiro; Korenaga, Toshinobu; Sakai, Takashi.

In: Organic Letters, Vol. 7, No. 18, 01.09.2005, p. 3985-3988.

Research output: Contribution to journalArticle

Ema, T, Ouchi, N, Doi, T, Korenaga, T & Sakai, T 2005, 'Highly sensitive chiral shift reagent bearing two zinc porphyrins', Organic Letters, vol. 7, no. 18, pp. 3985-3988. https://doi.org/10.1021/ol0514808
Ema, Tadashi ; Ouchi, Nozomi ; Doi, Tokuhiro ; Korenaga, Toshinobu ; Sakai, Takashi. / Highly sensitive chiral shift reagent bearing two zinc porphyrins. In: Organic Letters. 2005 ; Vol. 7, No. 18. pp. 3985-3988.
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