New bifunctional chemical catalysts for the hydration of nitriles are described. cis-Ru(acac)2(PPh2py)2 exhibited high activity, with a turnover frequency of up to 20,900 (mol of amide)/((mol of catalyst)h). Newly synthesized iridium complexes bearing a PPh2py ligand have a 16 e" square planar structure. The catalytic hydration of nitriles proceeded at 80 °C within few hours to give corresponding amides in almost quantitative yield. Moreover, the iridium complexes acted as a catalyst for the hydration under solvent-free conditions. In addition, new catalysts based on palladium nanoparticles for the hydration are described. Copper compounds containing oxygen atom acted as effective co-catalysts in the catalytic system.
|Number of pages||11|
|Journal||Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry|
|Publication status||Published - Jan 1 2010|
- Homogeneous catalyst catalysis
ASJC Scopus subject areas
- Organic Chemistry