Highly Enantioselective and Efficient Synthesis of Methyl (R)-o-Chloromandelate, Key Intermediate for Clopidogrel Synthesis, with Recombinant Escherichia coli.

David Pollard; Matthew Truppo; Jeffrey Moore; Birgit Kosjek; David Tellers; Jeffrey Moore; Ioulia Smonou; Dimitris Kalaitzakis; Musa M. Musa; Karla I. Ziegelmann-Fjeld; Claire Vieille; J. Gregory Zeikus; Robert S. Phillipsa; Matthew Truppo; Krista Morley; Paul Devine; Tadashi Ema; Nobuyasu Okita; Sayaka Ide; Takashi Sakai

doi:10.1002/9780470748589.ch8

Highly Enantioselective and Efficient Synthesis of Methyl (R)-o-Chloromandelate, Key Intermediate for Clopidogrel Synthesis, with Recombinant Escherichia coli.

David Pollard, Matthew Truppo, Jeffrey Moore, Birgit Kosjek, David Tellers, Jeffrey Moore, Ioulia Smonou, Dimitris Kalaitzakis, Musa M. Musa, Karla I. Ziegelmann-Fjeld, Claire Vieille, J. Gregory Zeikus, Robert S. Phillipsa, Matthew Truppo, Krista Morley, Paul Devine, Tadashi Ema, Nobuyasu Okita, Sayaka Ide, Takashi Sakai

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Original language	English
Title of host publication	Practical Methods for Biocatalysis and Biotransformations
Publisher	John Wiley & Sons, Ltd
Pages	291-294
Number of pages	4
ISBN (Print)	9780470519271
DOIs	https://doi.org/10.1002/9780470748589.ch8
Publication status	Published - Dec 15 2009

Keywords

Nicotinamide adenine dinucleotidephosphate(NADPH)-dependent ketoreductases(KREDs)
Synthesis of chiral sec-alcohols by ketone reduction

ASJC Scopus subject areas

Chemical Engineering(all)

Access to Document

10.1002/9780470748589.ch8

Cite this

Pollard, D., Truppo, M., Moore, J., Kosjek, B., Tellers, D., Moore, J., Smonou, I., Kalaitzakis, D., Musa, M. M., Ziegelmann-Fjeld, K. I., Vieille, C., Zeikus, J. G., Phillipsa, R. S., Truppo, M., Morley, K., Devine, P., Ema, T., Okita, N., Ide, S., & Sakai, T. (2009). Highly Enantioselective and Efficient Synthesis of Methyl (R)-o-Chloromandelate, Key Intermediate for Clopidogrel Synthesis, with Recombinant Escherichia coli. In Practical Methods for Biocatalysis and Biotransformations (pp. 291-294). John Wiley & Sons, Ltd. https://doi.org/10.1002/9780470748589.ch8

Highly Enantioselective and Efficient Synthesis of Methyl (R)-o-Chloromandelate, Key Intermediate for Clopidogrel Synthesis, with Recombinant Escherichia coli. / Pollard, David; Truppo, Matthew; Moore, Jeffrey et al.

Practical Methods for Biocatalysis and Biotransformations. John Wiley & Sons, Ltd, 2009. p. 291-294.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Pollard, D, Truppo, M, Moore, J, Kosjek, B, Tellers, D, Moore, J, Smonou, I, Kalaitzakis, D, Musa, MM, Ziegelmann-Fjeld, KI, Vieille, C, Zeikus, JG, Phillipsa, RS, Truppo, M, Morley, K, Devine, P, Ema, T, Okita, N, Ide, S & Sakai, T 2009, Highly Enantioselective and Efficient Synthesis of Methyl (R)-o-Chloromandelate, Key Intermediate for Clopidogrel Synthesis, with Recombinant Escherichia coli. in Practical Methods for Biocatalysis and Biotransformations. John Wiley & Sons, Ltd, pp. 291-294. https://doi.org/10.1002/9780470748589.ch8

@inbook{ff29e9fe7cb14faa883431c84f56f3de,

title = "Highly Enantioselective and Efficient Synthesis of Methyl (R)-o-Chloromandelate, Key Intermediate for Clopidogrel Synthesis, with Recombinant Escherichia coli.",

keywords = "Nicotinamide adenine dinucleotidephosphate(NADPH)-dependent ketoreductases(KREDs), Synthesis of chiral sec-alcohols by ketone reduction",

author = "David Pollard and Matthew Truppo and Jeffrey Moore and Birgit Kosjek and David Tellers and Jeffrey Moore and Ioulia Smonou and Dimitris Kalaitzakis and Musa, {Musa M.} and Ziegelmann-Fjeld, {Karla I.} and Claire Vieille and Zeikus, {J. Gregory} and Phillipsa, {Robert S.} and Matthew Truppo and Krista Morley and Paul Devine and Tadashi Ema and Nobuyasu Okita and Sayaka Ide and Takashi Sakai",

year = "2009",

month = dec,

day = "15",

doi = "10.1002/9780470748589.ch8",

language = "English",

isbn = "9780470519271",

pages = "291--294",

booktitle = "Practical Methods for Biocatalysis and Biotransformations",

publisher = "John Wiley & Sons, Ltd",

}

TY - CHAP

T1 - Highly Enantioselective and Efficient Synthesis of Methyl (R)-o-Chloromandelate, Key Intermediate for Clopidogrel Synthesis, with Recombinant Escherichia coli.

AU - Pollard, David

AU - Truppo, Matthew

AU - Moore, Jeffrey

AU - Kosjek, Birgit

AU - Tellers, David

AU - Moore, Jeffrey

AU - Smonou, Ioulia

AU - Kalaitzakis, Dimitris

AU - Musa, Musa M.

AU - Ziegelmann-Fjeld, Karla I.

AU - Vieille, Claire

AU - Zeikus, J. Gregory

AU - Phillipsa, Robert S.

AU - Truppo, Matthew

AU - Morley, Krista

AU - Devine, Paul

AU - Ema, Tadashi

AU - Okita, Nobuyasu

AU - Ide, Sayaka

AU - Sakai, Takashi

PY - 2009/12/15

Y1 - 2009/12/15

KW - Nicotinamide adenine dinucleotidephosphate(NADPH)-dependent ketoreductases(KREDs)

KW - Synthesis of chiral sec-alcohols by ketone reduction

UR - http://www.scopus.com/inward/record.url?scp=84889303034&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84889303034&partnerID=8YFLogxK

U2 - 10.1002/9780470748589.ch8

DO - 10.1002/9780470748589.ch8

M3 - Chapter

AN - SCOPUS:84889303034

SN - 9780470519271

SP - 291

EP - 294

BT - Practical Methods for Biocatalysis and Biotransformations

PB - John Wiley & Sons, Ltd

ER -

Highly Enantioselective and Efficient Synthesis of Methyl (R)-o-Chloromandelate, Key Intermediate for Clopidogrel Synthesis, with Recombinant Escherichia coli.

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Cite this