Highly dynamic self-organizing SMG morphogenesis in 3D culture

Mahmoud Farahat, Gulsan Ara Sathi, Hiroaki Taketa, Masamitsu Oshima, Takuo Kuboki, Takuya Matsumoto

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Biological tissues have specific cell patterns and well-organized structures which result from various organogenesis processes. Among which is branching morphogenesis which is the key developmental processes for many glandular tissues including lungs, kidney, salivary gland and liver. Many approaches were suggested to regenerate salivary gland tissue in vitro. Here, we developed a 3D culture technique to study and recapitulate the dynamic forces generated during SMG organogenesis by utilizing time lapse live imaging to monitor the cellular migration and reorganization process of both epithelium and mesenchyme cells.

Original languageEnglish
Title of host publication2015 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2015
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Print)9781479966783
DOIs
Publication statusPublished - Mar 21 2016
EventInternational Symposium on Micro-NanoMechatronics and Human Science, MHS 2015 - Nagoya, Japan
Duration: Nov 23 2015Nov 25 2015

Other

OtherInternational Symposium on Micro-NanoMechatronics and Human Science, MHS 2015
CountryJapan
CityNagoya
Period11/23/1511/25/15

    Fingerprint

ASJC Scopus subject areas

  • Biomedical Engineering
  • Electrical and Electronic Engineering
  • Biotechnology
  • Education

Cite this

Farahat, M., Sathi, G. A., Taketa, H., Oshima, M., Kuboki, T., & Matsumoto, T. (2016). Highly dynamic self-organizing SMG morphogenesis in 3D culture. In 2015 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2015 [7438259] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/MHS.2015.7438259