High-salt effects on the structure and damage of chromosomal DNA in Halobacterium salinarium, an extremely halophilic bacterium.

H. R. Shahmohammadi, H. Terato, E. Asgarani, T. Saito, H. Fumamizu, Y. Ohyama, K. Gekko, H. Ide

Research output: Contribution to journalArticle

Abstract

High concentration salt effects on the structure and radiation-induced damages of DNA were studied to elucidate the biochemical mechanism of the resistance of halophilic H. salinarium against DNA damaging agents. High concentration of KCl did not induce significant conformational changes in H. salinarium chromosomal DNA, but exhibited an extensive protective effect on the radiation-induced single-strand breaks of plasmid DNA.

Original languageEnglish
Pages (from-to)163-164
Number of pages2
JournalNucleic acids symposium series
Issue number37
Publication statusPublished - 1997
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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    Shahmohammadi, H. R., Terato, H., Asgarani, E., Saito, T., Fumamizu, H., Ohyama, Y., Gekko, K., & Ide, H. (1997). High-salt effects on the structure and damage of chromosomal DNA in Halobacterium salinarium, an extremely halophilic bacterium. Nucleic acids symposium series, (37), 163-164.