High-salt effects on the structure and damage of chromosomal DNA in Halobacterium salinarium, an extremely halophilic bacterium.

H. R. Shahmohammadi; H. Terato; E. Asgarani; T. Saito; H. Fumamizu; Y. Ohyama; K. Gekko; H. Ide

High-salt effects on the structure and damage of chromosomal DNA in Halobacterium salinarium, an extremely halophilic bacterium.

H. R. Shahmohammadi, H. Terato, E. Asgarani, T. Saito, H. Fumamizu, Y. Ohyama, K. Gekko, H. Ide

Research output: Contribution to journal › Article › peer-review

Abstract

High concentration salt effects on the structure and radiation-induced damages of DNA were studied to elucidate the biochemical mechanism of the resistance of halophilic H. salinarium against DNA damaging agents. High concentration of KCl did not induce significant conformational changes in H. salinarium chromosomal DNA, but exhibited an extensive protective effect on the radiation-induced single-strand breaks of plasmid DNA.

Original language	English
Pages (from-to)	163-164
Number of pages	2
Journal	Nucleic acids symposium series
Issue number	37
Publication status	Published - 1997
Externally published	Yes

ASJC Scopus subject areas

Medicine(all)

Cite this

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title = "High-salt effects on the structure and damage of chromosomal DNA in Halobacterium salinarium, an extremely halophilic bacterium.",

abstract = "High concentration salt effects on the structure and radiation-induced damages of DNA were studied to elucidate the biochemical mechanism of the resistance of halophilic H. salinarium against DNA damaging agents. High concentration of KCl did not induce significant conformational changes in H. salinarium chromosomal DNA, but exhibited an extensive protective effect on the radiation-induced single-strand breaks of plasmid DNA.",

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AU - Shahmohammadi, H. R.

AU - Terato, H.

AU - Asgarani, E.

AU - Saito, T.

AU - Fumamizu, H.

AU - Ohyama, Y.

AU - Gekko, K.

AU - Ide, H.

PY - 1997

Y1 - 1997

N2 - High concentration salt effects on the structure and radiation-induced damages of DNA were studied to elucidate the biochemical mechanism of the resistance of halophilic H. salinarium against DNA damaging agents. High concentration of KCl did not induce significant conformational changes in H. salinarium chromosomal DNA, but exhibited an extensive protective effect on the radiation-induced single-strand breaks of plasmid DNA.

AB - High concentration salt effects on the structure and radiation-induced damages of DNA were studied to elucidate the biochemical mechanism of the resistance of halophilic H. salinarium against DNA damaging agents. High concentration of KCl did not induce significant conformational changes in H. salinarium chromosomal DNA, but exhibited an extensive protective effect on the radiation-induced single-strand breaks of plasmid DNA.

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AN - SCOPUS:0031313188

SN - 0261-3166

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JO - Nucleic acids symposium series

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ER -

High-salt effects on the structure and damage of chromosomal DNA in Halobacterium salinarium, an extremely halophilic bacterium.

Abstract

ASJC Scopus subject areas

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