TY - JOUR
T1 - High-frequency oscillations of ictal muscle activity and epileptogenic discharges on intracranial EEG in a temporal lobe epilepsy patient
AU - Otsubo, Hiroshi
AU - Ochi, Ayako
AU - Imai, Katsumi
AU - Akiyama, Tomoyuki
AU - Fujimoto, Ayataka
AU - Go, Cristina
AU - Dirks, Peter
AU - Donner, Elizabeth J.
PY - 2008/4
Y1 - 2008/4
N2 - Objective: During seizures, intracranial EEG electrodes can record ictal muscle movements. Our purpose was to differentiate the high-frequency oscillations (HFOs) of extracranial muscle contractions from those of intracranial epileptogenic discharges. Methods: Using intracranial video-EEG (IVEEG), we recorded seizures in a 17-year-old boy with left mesial-temporal lobe epilepsy. We used multiple band frequency analysis (MBFA) to differentiate extracranial HFOs of craniofacial muscle activities from intracranial HFOs recorded ictally and interictally. Results: During 11 seizures, IVEEG showed low-amplitude fast waves (∼60 Hz) starting at the left mesial-temporal electrodes. Ictal facial grimacing projected low-amplitude (∼20 μV) fast waves (∼160 Hz) on inferior lateral-temporal electrodes. Interictal chewing projected medium-amplitude (∼100 μV) fast waves (∼140 Hz) correlating to mouth movements. MBFA topographic power spectrograms revealed a sustained, consistent ictal fast-frequency band from electrodes in the seizure-onset zone and randomly scattered HFOs without a specific frequency band from ictal and interictal extracranial muscle contractions. Conclusions: MBFA power spectrograms differentiated randomly scattered muscle HFOs without a specific frequency band at electrodes close to temporal muscles from ictal epileptic HFOs with a sustained, fast-frequency band in the seizure-onset zone. Significance: The pattern and distribution of frequency power spectrograms of extracranial HFOs differ from those of intracranial HFOs.
AB - Objective: During seizures, intracranial EEG electrodes can record ictal muscle movements. Our purpose was to differentiate the high-frequency oscillations (HFOs) of extracranial muscle contractions from those of intracranial epileptogenic discharges. Methods: Using intracranial video-EEG (IVEEG), we recorded seizures in a 17-year-old boy with left mesial-temporal lobe epilepsy. We used multiple band frequency analysis (MBFA) to differentiate extracranial HFOs of craniofacial muscle activities from intracranial HFOs recorded ictally and interictally. Results: During 11 seizures, IVEEG showed low-amplitude fast waves (∼60 Hz) starting at the left mesial-temporal electrodes. Ictal facial grimacing projected low-amplitude (∼20 μV) fast waves (∼160 Hz) on inferior lateral-temporal electrodes. Interictal chewing projected medium-amplitude (∼100 μV) fast waves (∼140 Hz) correlating to mouth movements. MBFA topographic power spectrograms revealed a sustained, consistent ictal fast-frequency band from electrodes in the seizure-onset zone and randomly scattered HFOs without a specific frequency band from ictal and interictal extracranial muscle contractions. Conclusions: MBFA power spectrograms differentiated randomly scattered muscle HFOs without a specific frequency band at electrodes close to temporal muscles from ictal epileptic HFOs with a sustained, fast-frequency band in the seizure-onset zone. Significance: The pattern and distribution of frequency power spectrograms of extracranial HFOs differ from those of intracranial HFOs.
KW - High-frequency oscillations
KW - Intracranial video-EEG
KW - Multiple band frequency analysis
KW - Muscle high-frequency oscillations
KW - Temporal lobe epilepsy
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U2 - 10.1016/j.clinph.2007.12.014
DO - 10.1016/j.clinph.2007.12.014
M3 - Article
C2 - 18289931
AN - SCOPUS:40649127394
VL - 119
SP - 862
EP - 868
JO - Electroencephalography and Clinical Neurophysiology - Electromyography and Motor Control
JF - Electroencephalography and Clinical Neurophysiology - Electromyography and Motor Control
SN - 1388-2457
IS - 4
ER -