Abstract
Objective: During seizures, intracranial EEG electrodes can record ictal muscle movements. Our purpose was to differentiate the high-frequency oscillations (HFOs) of extracranial muscle contractions from those of intracranial epileptogenic discharges. Methods: Using intracranial video-EEG (IVEEG), we recorded seizures in a 17-year-old boy with left mesial-temporal lobe epilepsy. We used multiple band frequency analysis (MBFA) to differentiate extracranial HFOs of craniofacial muscle activities from intracranial HFOs recorded ictally and interictally. Results: During 11 seizures, IVEEG showed low-amplitude fast waves (∼60 Hz) starting at the left mesial-temporal electrodes. Ictal facial grimacing projected low-amplitude (∼20 μV) fast waves (∼160 Hz) on inferior lateral-temporal electrodes. Interictal chewing projected medium-amplitude (∼100 μV) fast waves (∼140 Hz) correlating to mouth movements. MBFA topographic power spectrograms revealed a sustained, consistent ictal fast-frequency band from electrodes in the seizure-onset zone and randomly scattered HFOs without a specific frequency band from ictal and interictal extracranial muscle contractions. Conclusions: MBFA power spectrograms differentiated randomly scattered muscle HFOs without a specific frequency band at electrodes close to temporal muscles from ictal epileptic HFOs with a sustained, fast-frequency band in the seizure-onset zone. Significance: The pattern and distribution of frequency power spectrograms of extracranial HFOs differ from those of intracranial HFOs.
| Original language | English |
|---|---|
| Pages (from-to) | 862-868 |
| Number of pages | 7 |
| Journal | Clinical Neurophysiology |
| Volume | 119 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Apr 2008 |
| Externally published | Yes |
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Keywords
- High-frequency oscillations
- Intracranial video-EEG
- Multiple band frequency analysis
- Muscle high-frequency oscillations
- Temporal lobe epilepsy
ASJC Scopus subject areas
- Clinical Neurology
- Radiology Nuclear Medicine and imaging
- Neurology
- Sensory Systems
- Physiology (medical)
Cite this
High-frequency oscillations of ictal muscle activity and epileptogenic discharges on intracranial EEG in a temporal lobe epilepsy patient. / Otsubo, Hiroshi; Ochi, Ayako; Imai, Katsumi; Akiyama, Tomoyuki; Fujimoto, Ayataka; Go, Cristina; Dirks, Peter; Donner, Elizabeth J.
In: Clinical Neurophysiology, Vol. 119, No. 4, 04.2008, p. 862-868.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - High-frequency oscillations of ictal muscle activity and epileptogenic discharges on intracranial EEG in a temporal lobe epilepsy patient
AU - Otsubo, Hiroshi
AU - Ochi, Ayako
AU - Imai, Katsumi
AU - Akiyama, Tomoyuki
AU - Fujimoto, Ayataka
AU - Go, Cristina
AU - Dirks, Peter
AU - Donner, Elizabeth J.
PY - 2008/4
Y1 - 2008/4
N2 - Objective: During seizures, intracranial EEG electrodes can record ictal muscle movements. Our purpose was to differentiate the high-frequency oscillations (HFOs) of extracranial muscle contractions from those of intracranial epileptogenic discharges. Methods: Using intracranial video-EEG (IVEEG), we recorded seizures in a 17-year-old boy with left mesial-temporal lobe epilepsy. We used multiple band frequency analysis (MBFA) to differentiate extracranial HFOs of craniofacial muscle activities from intracranial HFOs recorded ictally and interictally. Results: During 11 seizures, IVEEG showed low-amplitude fast waves (∼60 Hz) starting at the left mesial-temporal electrodes. Ictal facial grimacing projected low-amplitude (∼20 μV) fast waves (∼160 Hz) on inferior lateral-temporal electrodes. Interictal chewing projected medium-amplitude (∼100 μV) fast waves (∼140 Hz) correlating to mouth movements. MBFA topographic power spectrograms revealed a sustained, consistent ictal fast-frequency band from electrodes in the seizure-onset zone and randomly scattered HFOs without a specific frequency band from ictal and interictal extracranial muscle contractions. Conclusions: MBFA power spectrograms differentiated randomly scattered muscle HFOs without a specific frequency band at electrodes close to temporal muscles from ictal epileptic HFOs with a sustained, fast-frequency band in the seizure-onset zone. Significance: The pattern and distribution of frequency power spectrograms of extracranial HFOs differ from those of intracranial HFOs.
AB - Objective: During seizures, intracranial EEG electrodes can record ictal muscle movements. Our purpose was to differentiate the high-frequency oscillations (HFOs) of extracranial muscle contractions from those of intracranial epileptogenic discharges. Methods: Using intracranial video-EEG (IVEEG), we recorded seizures in a 17-year-old boy with left mesial-temporal lobe epilepsy. We used multiple band frequency analysis (MBFA) to differentiate extracranial HFOs of craniofacial muscle activities from intracranial HFOs recorded ictally and interictally. Results: During 11 seizures, IVEEG showed low-amplitude fast waves (∼60 Hz) starting at the left mesial-temporal electrodes. Ictal facial grimacing projected low-amplitude (∼20 μV) fast waves (∼160 Hz) on inferior lateral-temporal electrodes. Interictal chewing projected medium-amplitude (∼100 μV) fast waves (∼140 Hz) correlating to mouth movements. MBFA topographic power spectrograms revealed a sustained, consistent ictal fast-frequency band from electrodes in the seizure-onset zone and randomly scattered HFOs without a specific frequency band from ictal and interictal extracranial muscle contractions. Conclusions: MBFA power spectrograms differentiated randomly scattered muscle HFOs without a specific frequency band at electrodes close to temporal muscles from ictal epileptic HFOs with a sustained, fast-frequency band in the seizure-onset zone. Significance: The pattern and distribution of frequency power spectrograms of extracranial HFOs differ from those of intracranial HFOs.
KW - High-frequency oscillations
KW - Intracranial video-EEG
KW - Multiple band frequency analysis
KW - Muscle high-frequency oscillations
KW - Temporal lobe epilepsy
UR - http://www.scopus.com/inward/record.url?scp=40649127394&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=40649127394&partnerID=8YFLogxK
U2 - 10.1016/j.clinph.2007.12.014
DO - 10.1016/j.clinph.2007.12.014
M3 - Article
VL - 119
SP - 862
EP - 868
JO - Clinical Neurophysiology
JF - Clinical Neurophysiology
SN - 1388-2457
IS - 4
ER -