High-cut characteristics of the baroreflex neural arc in rats

Toru Kawada, Shuji Shimizu, Meihua Li, Can Zheng, Kazunori Uemura, Atsunori Kamiya, Masaru Sugimachi

Research output: Contribution to journalArticle

Abstract

The arterial baroreflex system may be divided into the neural arc (from pressure input to efferent sympathetic nerve activity) and the peripheral arc (from sympathetic nerve activity to arterial pressure). In rabbits, the baroreflex neural arc reveals derivative characteristics in the frequency range below 0.8 Hz and high-cut characteristics above 0.8 Hz. To examine such high-cut characteristics are also present in rats, we isolated the carotid sinus regions in anesthetized rats (n = 5) and imposed a Gaussian white noise input with a switching interval of 50 ms. The transfer function of the baroreflex neural arc showed derivative characteristics in the frequency range from 0.1 to 1.3 Hz and high-cut characteristics above 1.3 Hz in rats. These results indicate that the baroreflex neural arc possesses high-cut characteristics in rats as well as in rabbits, which may contribute to preserving baroreflex gain against pulsatile pressure.

Original languageEnglish
Pages (from-to)O-406-O-407
JournalTransactions of Japanese Society for Medical and Biological Engineering
Volume52
DOIs
Publication statusPublished - Jan 1 2014
Externally publishedYes

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Rats
Derivatives
White noise
Transfer functions

Keywords

  • Baroreflex
  • Transfer function
  • White noise analysis

ASJC Scopus subject areas

  • Biomedical Engineering

Cite this

High-cut characteristics of the baroreflex neural arc in rats. / Kawada, Toru; Shimizu, Shuji; Li, Meihua; Zheng, Can; Uemura, Kazunori; Kamiya, Atsunori; Sugimachi, Masaru.

In: Transactions of Japanese Society for Medical and Biological Engineering, Vol. 52, 01.01.2014, p. O-406-O-407.

Research output: Contribution to journalArticle

Kawada, Toru ; Shimizu, Shuji ; Li, Meihua ; Zheng, Can ; Uemura, Kazunori ; Kamiya, Atsunori ; Sugimachi, Masaru. / High-cut characteristics of the baroreflex neural arc in rats. In: Transactions of Japanese Society for Medical and Biological Engineering. 2014 ; Vol. 52. pp. O-406-O-407.
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