Hepatic artery reconstruction following ablative surgery for hepatobiliary and pancreatic malignancies

M. Sakuraba, S. Miyamoto, S. Nagamatsu, S. Kayano, M. Taji, T. Kinoshita, T. Kosuge, Yoshihiro Kimata

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Objective: Hepatic artery (HA) reconstruction is an important part of resective surgery for advanced hepatobiliary and pancreatic malignancies, but few reports have been published. To identify indications for HA reconstruction, we retrospectively analyzed our surgical procedures and outcomes. Methods: En-bloc resection of advanced hepatobiliary and pancreatic malignancies followed by HA reconstruction was performed in 35 patients. Patients ranged in age from 27 to 81 years and included 18 men and 17 women. The primary site of cancer included the bile duct in 22 patients, the pancreas in 7, and others in 6. Reconstruction of the HA was necessitated by HA resection due to direct cancer invasion in 29 patients and by accidental arterial injury during surgical procedure in 6 patients. Results: The HA was reconstructed with end-to-end anastomosis between hepatic arteries in 17 patients. Transposition of an intra-abdominal artery, such as the gastroepiploic artery, was required in 14 patients, and arterial grafting was required in 4 patients. Although the HA patency was achieved in 30 patients, 4 cases of arterial thrombosis and 1 case of arterial rupture developed postoperatively. The overall RFS time was analyzed in all patients, and mean and median RFS times were 18 and 9 months, respectively. Conclusion: Although oncologic outcomes remain poor, HA resection and reconstruction can be performed in selected patients. We believe that the method of first choice for HA reconstruction is end-to-end anastomosis between HAs. A vascular autograft should be used only in selected cases.

Original languageEnglish
Pages (from-to)580-585
Number of pages6
JournalEuropean Journal of Surgical Oncology
Volume38
Issue number7
DOIs
Publication statusPublished - Jul 2012

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Hepatic Artery
Neoplasms
Gastroepiploic Artery
Bile Duct Neoplasms
Intraoperative Complications
Autografts
Blood Vessels
Rupture
Pancreas
Thrombosis
Arteries

Keywords

  • Arterial graft
  • Hepatic artery
  • Hepatic artery reconstruction
  • Hepatobiliary malignancy

ASJC Scopus subject areas

  • Oncology
  • Surgery

Cite this

Hepatic artery reconstruction following ablative surgery for hepatobiliary and pancreatic malignancies. / Sakuraba, M.; Miyamoto, S.; Nagamatsu, S.; Kayano, S.; Taji, M.; Kinoshita, T.; Kosuge, T.; Kimata, Yoshihiro.

In: European Journal of Surgical Oncology, Vol. 38, No. 7, 07.2012, p. 580-585.

Research output: Contribution to journalArticle

Sakuraba, M. ; Miyamoto, S. ; Nagamatsu, S. ; Kayano, S. ; Taji, M. ; Kinoshita, T. ; Kosuge, T. ; Kimata, Yoshihiro. / Hepatic artery reconstruction following ablative surgery for hepatobiliary and pancreatic malignancies. In: European Journal of Surgical Oncology. 2012 ; Vol. 38, No. 7. pp. 580-585.
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