Hepatic and gastric involvement in a case of systemic sarcoidosis presenting with rupture of esophageal varices

Hiroaki Saito; Masayasu Ohmori; Masaya Iwamuro; Takehiro Tanaka; Nozomu Wada; Tetsuya Yasunaka; Akinobu Takaki; Hiroyuki Okada

doi:10.2169/internalmedicine.8768-16

Hepatic and gastric involvement in a case of systemic sarcoidosis presenting with rupture of esophageal varices

Hiroaki Saito, Masayasu Ohmori, Masaya Iwamuro, Takehiro Tanaka, Nozomu Wada, Tetsuya Yasunaka, Akinobu Takaki, Hiroyuki Okada

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

A 46-year-old woman presented with massive hematemesis, caused by the rupture of esophageal varices. The laboratory investigations showed pancytopenia, and imaging tests revealed hepatosplenomegaly and ascites. A diagnosis of systemic sarcoidosis was made based on biopsies of the liver, stomach, lungs, heart, and skin. Although fat deposition was predominant, non-caseating granuloma and cirrhotic changes were found in the liver. Non-caseating granuloma was also identified in a biopsy specimen from minute depressions of the gastric folds. This case illustrates the rare involvement of the digestive system in a case of systemic sarcoidosis.

Original language	English
Pages (from-to)	2583-2588
Number of pages	6
Journal	Internal Medicine
Volume	56
Issue number	19
DOIs	https://doi.org/10.2169/internalmedicine.8768-16
Publication status	Published - 2017

Keywords

Esophagogastroduodenoscopy
Gastric involvement
Hepatic involvement
Laparoscopy
Systemic sarcoidosis

ASJC Scopus subject areas

Internal Medicine

Access to Document

10.2169/internalmedicine.8768-16

Cite this

@article{00572b41b8fc4699a7a40454da2adb8f,

title = "Hepatic and gastric involvement in a case of systemic sarcoidosis presenting with rupture of esophageal varices",

abstract = "A 46-year-old woman presented with massive hematemesis, caused by the rupture of esophageal varices. The laboratory investigations showed pancytopenia, and imaging tests revealed hepatosplenomegaly and ascites. A diagnosis of systemic sarcoidosis was made based on biopsies of the liver, stomach, lungs, heart, and skin. Although fat deposition was predominant, non-caseating granuloma and cirrhotic changes were found in the liver. Non-caseating granuloma was also identified in a biopsy specimen from minute depressions of the gastric folds. This case illustrates the rare involvement of the digestive system in a case of systemic sarcoidosis.",

keywords = "Esophagogastroduodenoscopy, Gastric involvement, Hepatic involvement, Laparoscopy, Systemic sarcoidosis",

author = "Hiroaki Saito and Masayasu Ohmori and Masaya Iwamuro and Takehiro Tanaka and Nozomu Wada and Tetsuya Yasunaka and Akinobu Takaki and Hiroyuki Okada",

note = "Publisher Copyright: {\textcopyright} 2017 The Japanese Society of Internal Medicine.",

year = "2017",

doi = "10.2169/internalmedicine.8768-16",

language = "English",

volume = "56",

pages = "2583--2588",

journal = "Internal Medicine",

issn = "0918-2918",

publisher = "Japanese Society of Internal Medicine",

number = "19",

}

TY - JOUR

T1 - Hepatic and gastric involvement in a case of systemic sarcoidosis presenting with rupture of esophageal varices

AU - Saito, Hiroaki

AU - Ohmori, Masayasu

AU - Iwamuro, Masaya

AU - Tanaka, Takehiro

AU - Wada, Nozomu

AU - Yasunaka, Tetsuya

AU - Takaki, Akinobu

AU - Okada, Hiroyuki

PY - 2017

Y1 - 2017

N2 - A 46-year-old woman presented with massive hematemesis, caused by the rupture of esophageal varices. The laboratory investigations showed pancytopenia, and imaging tests revealed hepatosplenomegaly and ascites. A diagnosis of systemic sarcoidosis was made based on biopsies of the liver, stomach, lungs, heart, and skin. Although fat deposition was predominant, non-caseating granuloma and cirrhotic changes were found in the liver. Non-caseating granuloma was also identified in a biopsy specimen from minute depressions of the gastric folds. This case illustrates the rare involvement of the digestive system in a case of systemic sarcoidosis.

AB - A 46-year-old woman presented with massive hematemesis, caused by the rupture of esophageal varices. The laboratory investigations showed pancytopenia, and imaging tests revealed hepatosplenomegaly and ascites. A diagnosis of systemic sarcoidosis was made based on biopsies of the liver, stomach, lungs, heart, and skin. Although fat deposition was predominant, non-caseating granuloma and cirrhotic changes were found in the liver. Non-caseating granuloma was also identified in a biopsy specimen from minute depressions of the gastric folds. This case illustrates the rare involvement of the digestive system in a case of systemic sarcoidosis.

KW - Esophagogastroduodenoscopy

KW - Gastric involvement

KW - Hepatic involvement

KW - Laparoscopy

KW - Systemic sarcoidosis

UR - http://www.scopus.com/inward/record.url?scp=85030563523&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85030563523&partnerID=8YFLogxK

U2 - 10.2169/internalmedicine.8768-16

DO - 10.2169/internalmedicine.8768-16

M3 - Article

C2 - 28883247

AN - SCOPUS:85030563523

SN - 0918-2918

VL - 56

SP - 2583

EP - 2588

JO - Internal Medicine

JF - Internal Medicine

IS - 19

ER -

Hepatic and gastric involvement in a case of systemic sarcoidosis presenting with rupture of esophageal varices

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this