Hepatic and gastric involvement in a case of systemic sarcoidosis presenting with rupture of esophageal varices

Hiroaki Saito, Masayasu Ohmori, Masaya Iwamuro, Takehiro Tanaka, Nozomu Wada, Tetsuya Yasunaka, Akinobu Takaki, Hiroyuki Okada

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3 Citations (Scopus)


A 46-year-old woman presented with massive hematemesis, caused by the rupture of esophageal varices. The laboratory investigations showed pancytopenia, and imaging tests revealed hepatosplenomegaly and ascites. A diagnosis of systemic sarcoidosis was made based on biopsies of the liver, stomach, lungs, heart, and skin. Although fat deposition was predominant, non-caseating granuloma and cirrhotic changes were found in the liver. Non-caseating granuloma was also identified in a biopsy specimen from minute depressions of the gastric folds. This case illustrates the rare involvement of the digestive system in a case of systemic sarcoidosis.

Original languageEnglish
Pages (from-to)2583-2588
Number of pages6
JournalInternal Medicine
Issue number19
Publication statusPublished - 2017



  • Esophagogastroduodenoscopy
  • Gastric involvement
  • Hepatic involvement
  • Laparoscopy
  • Systemic sarcoidosis

ASJC Scopus subject areas

  • Internal Medicine

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