Hemodynamics of microvascular dysfunction in patients with anterior wall acute myocardial infarction

Hiroshi Ito, Kazuo Terai, Katsuomi Iwakura, Ichiro Kawase, Kenshi Fujii

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

This study investigated whether the no-reflow phenomenon in acute myocardial infarction (AMI) is associated with an increase in coronary zero flow pressure (ZFP), a decrease in coronary arterial conductance, or both phenomena. Coronary blood flow velocity and pressure were measured with a Doppler guidewire and a pressure wire, respectively, during vasodilation with adenosine triphosphate after coronary intervention. The data indicate that the no-reflow phenomenon is not necessarily associated with a decrease in coronary arterial conductance but with an increase in ZFP. Greater ZFP is associated with more severe microvascular dysfunction and worse functional outcomes in patients with AMI.

Original languageEnglish
Pages (from-to)209-212
Number of pages4
JournalAmerican Journal of Cardiology
Volume94
Issue number2
DOIs
Publication statusPublished - Jul 15 2004
Externally publishedYes

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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