Hemodynamics of microvascular dysfunction in patients with anterior wall acute myocardial infarction

Hiroshi Ito; Kazuo Terai; Katsuomi Iwakura; Ichiro Kawase; Kenshi Fujii

doi:10.1016/j.amjcard.2004.03.066

Hemodynamics of microvascular dysfunction in patients with anterior wall acute myocardial infarction

Hiroshi Ito, Kazuo Terai, Katsuomi Iwakura, Ichiro Kawase, Kenshi Fujii

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

Abstract

This study investigated whether the no-reflow phenomenon in acute myocardial infarction (AMI) is associated with an increase in coronary zero flow pressure (ZFP), a decrease in coronary arterial conductance, or both phenomena. Coronary blood flow velocity and pressure were measured with a Doppler guidewire and a pressure wire, respectively, during vasodilation with adenosine triphosphate after coronary intervention. The data indicate that the no-reflow phenomenon is not necessarily associated with a decrease in coronary arterial conductance but with an increase in ZFP. Greater ZFP is associated with more severe microvascular dysfunction and worse functional outcomes in patients with AMI.

Original language	English
Pages (from-to)	209-212
Number of pages	4
Journal	American Journal of Cardiology
Volume	94
Issue number	2
DOIs	https://doi.org/10.1016/j.amjcard.2004.03.066
Publication status	Published - Jul 15 2004
Externally published	Yes

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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title = "Hemodynamics of microvascular dysfunction in patients with anterior wall acute myocardial infarction",

abstract = "This study investigated whether the no-reflow phenomenon in acute myocardial infarction (AMI) is associated with an increase in coronary zero flow pressure (ZFP), a decrease in coronary arterial conductance, or both phenomena. Coronary blood flow velocity and pressure were measured with a Doppler guidewire and a pressure wire, respectively, during vasodilation with adenosine triphosphate after coronary intervention. The data indicate that the no-reflow phenomenon is not necessarily associated with a decrease in coronary arterial conductance but with an increase in ZFP. Greater ZFP is associated with more severe microvascular dysfunction and worse functional outcomes in patients with AMI.",

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AU - Ito, Hiroshi

AU - Terai, Kazuo

AU - Iwakura, Katsuomi

AU - Kawase, Ichiro

AU - Fujii, Kenshi

PY - 2004/7/15

Y1 - 2004/7/15

N2 - This study investigated whether the no-reflow phenomenon in acute myocardial infarction (AMI) is associated with an increase in coronary zero flow pressure (ZFP), a decrease in coronary arterial conductance, or both phenomena. Coronary blood flow velocity and pressure were measured with a Doppler guidewire and a pressure wire, respectively, during vasodilation with adenosine triphosphate after coronary intervention. The data indicate that the no-reflow phenomenon is not necessarily associated with a decrease in coronary arterial conductance but with an increase in ZFP. Greater ZFP is associated with more severe microvascular dysfunction and worse functional outcomes in patients with AMI.

AB - This study investigated whether the no-reflow phenomenon in acute myocardial infarction (AMI) is associated with an increase in coronary zero flow pressure (ZFP), a decrease in coronary arterial conductance, or both phenomena. Coronary blood flow velocity and pressure were measured with a Doppler guidewire and a pressure wire, respectively, during vasodilation with adenosine triphosphate after coronary intervention. The data indicate that the no-reflow phenomenon is not necessarily associated with a decrease in coronary arterial conductance but with an increase in ZFP. Greater ZFP is associated with more severe microvascular dysfunction and worse functional outcomes in patients with AMI.

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Hemodynamics of microvascular dysfunction in patients with anterior wall acute myocardial infarction

Abstract

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