Abstract
This study investigated whether the no-reflow phenomenon in acute myocardial infarction (AMI) is associated with an increase in coronary zero flow pressure (ZFP), a decrease in coronary arterial conductance, or both phenomena. Coronary blood flow velocity and pressure were measured with a Doppler guidewire and a pressure wire, respectively, during vasodilation with adenosine triphosphate after coronary intervention. The data indicate that the no-reflow phenomenon is not necessarily associated with a decrease in coronary arterial conductance but with an increase in ZFP. Greater ZFP is associated with more severe microvascular dysfunction and worse functional outcomes in patients with AMI.
| Original language | English |
|---|---|
| Pages (from-to) | 209-212 |
| Number of pages | 4 |
| Journal | American Journal of Cardiology |
| Volume | 94 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Jul 15 2004 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
Hemodynamics of microvascular dysfunction in patients with anterior wall acute myocardial infarction. / Itoh, Hiroshi; Terai, Kazuo; Iwakura, Katsuomi; Kawase, Ichiro; Fujii, Kenshi.
In: American Journal of Cardiology, Vol. 94, No. 2, 15.07.2004, p. 209-212.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Hemodynamics of microvascular dysfunction in patients with anterior wall acute myocardial infarction
AU - Itoh, Hiroshi
AU - Terai, Kazuo
AU - Iwakura, Katsuomi
AU - Kawase, Ichiro
AU - Fujii, Kenshi
PY - 2004/7/15
Y1 - 2004/7/15
N2 - This study investigated whether the no-reflow phenomenon in acute myocardial infarction (AMI) is associated with an increase in coronary zero flow pressure (ZFP), a decrease in coronary arterial conductance, or both phenomena. Coronary blood flow velocity and pressure were measured with a Doppler guidewire and a pressure wire, respectively, during vasodilation with adenosine triphosphate after coronary intervention. The data indicate that the no-reflow phenomenon is not necessarily associated with a decrease in coronary arterial conductance but with an increase in ZFP. Greater ZFP is associated with more severe microvascular dysfunction and worse functional outcomes in patients with AMI.
AB - This study investigated whether the no-reflow phenomenon in acute myocardial infarction (AMI) is associated with an increase in coronary zero flow pressure (ZFP), a decrease in coronary arterial conductance, or both phenomena. Coronary blood flow velocity and pressure were measured with a Doppler guidewire and a pressure wire, respectively, during vasodilation with adenosine triphosphate after coronary intervention. The data indicate that the no-reflow phenomenon is not necessarily associated with a decrease in coronary arterial conductance but with an increase in ZFP. Greater ZFP is associated with more severe microvascular dysfunction and worse functional outcomes in patients with AMI.
UR - http://www.scopus.com/inward/record.url?scp=3142647044&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=3142647044&partnerID=8YFLogxK
U2 - 10.1016/j.amjcard.2004.03.066
DO - 10.1016/j.amjcard.2004.03.066
M3 - Article
C2 - 15246904
AN - SCOPUS:3142647044
VL - 94
SP - 209
EP - 212
JO - American Journal of Cardiology
JF - American Journal of Cardiology
SN - 0002-9149
IS - 2
ER -