Abstract
Isoxazolidines that are useful precursors for β-amino acids have been prepared relying on intermolecular amino Michael addition-intramolecular S(N)2 displacement employing hydroxylamine or hydrate of ketone-based nitrone as an N- and O-centered binucleophile.
| Original language | English |
|---|---|
| Pages (from-to) | 2433-2448 |
| Number of pages | 16 |
| Journal | Tetrahedron |
| Volume | 54 |
| Issue number | 11 |
| DOIs | |
| Publication status | Published - Mar 12 1998 |
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ASJC Scopus subject areas
- Biochemistry
- Organic Chemistry
- Drug Discovery
Cite this
Hemiaminal generated by hydration of ketone-based nitrone as an N,O-centered nucleophile in organic synthesis. / Ishikawa, Teruhiko; Nagai, Keita; Senzaki, Mami; Tatsukawa, Akiko; Saito, Seiki.
In: Tetrahedron, Vol. 54, No. 11, 12.03.1998, p. 2433-2448.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Hemiaminal generated by hydration of ketone-based nitrone as an N,O-centered nucleophile in organic synthesis
AU - Ishikawa, Teruhiko
AU - Nagai, Keita
AU - Senzaki, Mami
AU - Tatsukawa, Akiko
AU - Saito, Seiki
PY - 1998/3/12
Y1 - 1998/3/12
N2 - Isoxazolidines that are useful precursors for β-amino acids have been prepared relying on intermolecular amino Michael addition-intramolecular S(N)2 displacement employing hydroxylamine or hydrate of ketone-based nitrone as an N- and O-centered binucleophile.
AB - Isoxazolidines that are useful precursors for β-amino acids have been prepared relying on intermolecular amino Michael addition-intramolecular S(N)2 displacement employing hydroxylamine or hydrate of ketone-based nitrone as an N- and O-centered binucleophile.
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UR - http://www.scopus.com/inward/citedby.url?scp=0032510258&partnerID=8YFLogxK
U2 - 10.1016/S0040-4020(98)00008-8
DO - 10.1016/S0040-4020(98)00008-8
M3 - Article
VL - 54
SP - 2433
EP - 2448
JO - Tetrahedron
JF - Tetrahedron
SN - 0040-4020
IS - 11
ER -