Abstract
Isoxazolidines that are useful precursors for β-amino acids have been prepared relying on intermolecular amino Michael addition-intramolecular S(N)2 displacement employing hydroxylamine or hydrate of ketone-based nitrone as an N- and O-centered binucleophile.
Original language | English |
---|---|
Pages (from-to) | 2433-2448 |
Number of pages | 16 |
Journal | Tetrahedron |
Volume | 54 |
Issue number | 11 |
DOIs | |
Publication status | Published - Mar 12 1998 |
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry