HEMA inhibits interfacial nano-layering of the functional monomer MDP

Y. Yoshida, K. Yoshihara, S. Hayakawa, N. Nagaoka, T. Okihara, T. Matsumoto, S. Minagi, A. Osaka, K. Van Landuyt, B. Van Meerbeek

Research output: Contribution to journalArticle

63 Citations (Scopus)

Abstract

Previous research showed that the functional monomer 10-methacryloxydecyl dihydrogen phosphate (MDP) ionically bonds to hydroxyapatite (HAp) and forms a nano- layered structure at the interface with HAp-based substrates. Such hydrophobic nano-layering is considered to contribute to the long-term durability of the bond to tooth tissue. However, dental adhesives are complex mixtures usually containing different monomers. This study investigated the effect of the monomer 2-hydroxyethylmethacrylate (HEMA) on the chemical interaction of MDP with HAp by x-ray diffraction (XRD), nuclear magnetic resonance (NMR), and quartz crystal microbalance (QCM). We examined the chemical interaction of 5 experimental MDP solutions with increasing concentrations of HEMA. XRD revealed that addition of HEMA inhibits nano-layering at the interface, while NMR confirmed that MDP remained adsorbed onto the HAp surface. QCM confirmed this adsorption of MDP to HAp, as well as revealed that the demineralization rate of HAp by MDP was reduced by HEMA. It was concluded that even though the adsorption of MDP to HAp was not hindered, addition of HEMA inhibited interfacial nano-layering. Potential consequences with regard to bond durability necessitate further research.

Original languageEnglish
Pages (from-to)1060-1065
Number of pages6
JournalJournal of dental research
Volume91
Issue number11
DOIs
Publication statusPublished - Nov 2012

Keywords

  • NMR
  • adhesive
  • bonding
  • hydroxyapatite
  • phosphoric acid ester monomer
  • x-ray diffraction

ASJC Scopus subject areas

  • Dentistry(all)

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