Heat shock protein-peptide complexes in cancer immunotherapy

Pramod K. Srivastava, Heiichiro Udono

Research output: Contribution to journalArticle

126 Citations (Scopus)

Abstract

Heat shock proteins (HSPs) are associated with a broad spectrum of peptides derived from the cells from which they are isolated. Vaccination with such HSP-peptide complexes elicits protective immunity against tumors or other cells used as the source of HSPs. These observations suggest that HSP-peptide complexes are suitable as vaccines against cancers and infectious diseases.

Original languageEnglish
Pages (from-to)728-732
Number of pages5
JournalCurrent Opinion in Immunology
Volume6
Issue number5
DOIs
Publication statusPublished - 1994
Externally publishedYes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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