Heart Failure Association of the ESC, Heart Failure Society of America and Japanese Heart Failure Society Position statement on endomyocardial biopsy

Petar M. Seferović, Hiroyuki Tsutsui, Dennis M. McNamara, Arsen D. Ristić, Cristina Basso, Biykem Bozkurt, Leslie T. Cooper, Gerasimos Filippatos, Tomomi Ide, Takayuki Inomata, Karin Klingel, Aleš Linhart, Alexander R. Lyon, Mandeep R. Mehra, Marija Polovina, Ivan Milinković, Kazufumi Nakamura, Stefan D. Anker, Ivana Veljić, Tomohito OhtaniTakahiro Okumura, Thomas Thum, Carsten Tschöpe, Giuseppe Rosano, Andrew J.S. Coats, Randall C. Starling

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

Endomyocardial biopsy (EMB) is an invasive procedure, globally most often used for the monitoring of heart transplant (HTx) rejection. In addition, EMB can have an important complementary role to the clinical assessment in establishing the diagnosis of diverse cardiac disorders, including myocarditis, cardiomyopathies, drug-related cardiotoxicity, amyloidosis, other infiltrative and storage disorders, and cardiac tumours. Improvements in EMB equipment and the development of new techniques for the analysis of EMB samples have significantly improved diagnostic precision of EMB. The present document is the result of the Trilateral Cooperation Project between the Heart Failure Association of the European Society of Cardiology, the Heart Failure Society of America, and the Japanese Heart Failure Society. It represents an expert consensus aiming to provide a comprehensive, up-to-date perspective on EMB, with a focus on the following main issues: (i) an overview of the practical approach to EMB, (ii) an update on indications for EMB, (iii) a revised plan for HTx rejection surveillance, (iv) the impact of multimodality imaging on EMB, and (v) the current clinical practice in the worldwide use of EMB.

Original languageEnglish
Pages (from-to)854-871
Number of pages18
JournalEuropean Journal of Heart Failure
Volume23
Issue number6
DOIs
Publication statusPublished - Jun 2021
Externally publishedYes

Keywords

  • Amyloidosis
  • Cardiac tumours
  • Cardiomyopathy
  • Cardiotoxicity
  • Endomyocardial biopsy
  • Heart failure
  • Heart transplantation
  • Myocarditis
  • Sarcoidosis

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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