Abstract
The application of a Hadamard transform technique to microchip electrophoresis is described. The sample is electrokinetically injected into a separation channel and is then detected by diode laser-induced fluorometry. The sample and buffer solutions are introduced into the channel by controlling the high voltages applied to the solutions, according to a code determined by a Hadamard matrix. The S/N ratio of the signal in the electropherogram can be improved by a factor of 5 in comparison with that obtained by a conventional single-injection method, although an 8-fold improvement is theoretically predicted when a 255-order matrix is used.
Original language | English |
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Pages (from-to) | 1765-1768 |
Number of pages | 4 |
Journal | Analytical Chemistry |
Volume | 75 |
Issue number | 7 |
DOIs | |
Publication status | Published - Apr 1 2003 |
Externally published | Yes |
ASJC Scopus subject areas
- Analytical Chemistry