TY - JOUR
T1 - Guidelines for management of idiopathic normal pressure hydrocephalus (Third edition)
T2 - Endorsed by the Japanese society of normal pressure hydrocephalus
AU - The research committee of idiopathic normal pressure hydrocephalus
AU - Nakajima, Madoka
AU - Yamada, Shigeki
AU - Miyajima, Masakazu
AU - Ishii, Kazunari
AU - Kuriyama, Nagato
AU - Kazui, Hiroaki
AU - Kanemoto, Hideki
AU - Suehiro, Takashi
AU - Yoshiyama, Kenji
AU - Kameda, Masahiro
AU - Kajimoto, Yoshinaga
AU - Mase, Mitsuhito
AU - Murai, Hisayuki
AU - Kita, Daisuke
AU - Kimura, Teruo
AU - Samejima, Naoyuki
AU - Tokuda, Takahiko
AU - Kaijima, Mitsunobu
AU - Akiba, Chihiro
AU - Kawamura, Kaito
AU - Atsuchi, Masamichi
AU - Hirata, Yoshihumi
AU - Matsumae, Mitsunori
AU - Sasaki, Makoto
AU - Yamashita, Fumio
AU - Aoki, Shigeki
AU - Irie, Ryusuke
AU - Miyake, Hiroji
AU - Kato, Takeo
AU - Mori, Etsuro
AU - Ishikawa, Masatsune
AU - Date, Isao
AU - Arai, Hajime
N1 - Funding Information:
We thank Dr. Kostadin Karagiozov for editing the manuscript. This work is supported by the Ministry of Health, Labour and Welfare of Japan Sciences Research Grants Subsidy for Intractable Diseases Policy Research Project (2017-Nanchi-General-037).
Publisher Copyright:
© 2021 by The Japan Neurosurgical Society.
PY - 2021
Y1 - 2021
N2 - Among the various disorders that manifest with gait disturbance, cognitive impairment, and urinary incontinence in the elderly population, idiopathic normal pressure hydrocephalus (iNPH) is becoming of great importance. The first edition of these guidelines for management of iNPH was published in 2004, and the second edition in 2012, to provide a series of timely, evidence-based recommendations related to iNPH. Since the last edition, clinical awareness of iNPH has risen dramatically, and clinical and basic research efforts on iNPH have increased significantly. This third edition of the guidelines was made to share these ideas with the international community and to promote international research on iNPH. The revision of the guidelines was undertaken by a multidisciplinary expert working group of the Japanese Society of Normal Pressure Hydro-cephalus in conjunction with the Japanese Ministry of Health, Labour and Welfare research project. This revision proposes a new classification for NPH. The category of iNPH is clearly distinguished from NPH with congenital/developmental and acquired etiologies. Additionally, the essential role of disproportionately enlarged subarachnoid-space hydrocephalus (DESH) in the imaging diagnosis and decision for further management of iNPH is discussed in this edition. We created an algorithm for diagnosis and decision for shunt management. Diagnosis by bio-markers that distinguish prognosis has been also initiated. Therefore, diagnosis and treatment of iNPH have entered a new phase. We hope that this third edition of the guidelines will help patients, their families, and healthcare professionals involved in treating iNPH.
AB - Among the various disorders that manifest with gait disturbance, cognitive impairment, and urinary incontinence in the elderly population, idiopathic normal pressure hydrocephalus (iNPH) is becoming of great importance. The first edition of these guidelines for management of iNPH was published in 2004, and the second edition in 2012, to provide a series of timely, evidence-based recommendations related to iNPH. Since the last edition, clinical awareness of iNPH has risen dramatically, and clinical and basic research efforts on iNPH have increased significantly. This third edition of the guidelines was made to share these ideas with the international community and to promote international research on iNPH. The revision of the guidelines was undertaken by a multidisciplinary expert working group of the Japanese Society of Normal Pressure Hydro-cephalus in conjunction with the Japanese Ministry of Health, Labour and Welfare research project. This revision proposes a new classification for NPH. The category of iNPH is clearly distinguished from NPH with congenital/developmental and acquired etiologies. Additionally, the essential role of disproportionately enlarged subarachnoid-space hydrocephalus (DESH) in the imaging diagnosis and decision for further management of iNPH is discussed in this edition. We created an algorithm for diagnosis and decision for shunt management. Diagnosis by bio-markers that distinguish prognosis has been also initiated. Therefore, diagnosis and treatment of iNPH have entered a new phase. We hope that this third edition of the guidelines will help patients, their families, and healthcare professionals involved in treating iNPH.
KW - Clinical guideline
KW - Diagnosis
KW - Idiopathic normal pressure hydrocephalus
KW - Management
KW - Treatment
UR - http://www.scopus.com/inward/record.url?scp=85102032899&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85102032899&partnerID=8YFLogxK
U2 - 10.2176/nmc.st.2020-0292
DO - 10.2176/nmc.st.2020-0292
M3 - Article
C2 - 33455998
AN - SCOPUS:85102032899
VL - 61
SP - 63
EP - 97
JO - Neurologia Medico-Chirurgica
JF - Neurologia Medico-Chirurgica
SN - 0470-8105
IS - 2
ER -