Granulocytic sarcoma with orbit, caude equina, muscle and peripheral nerve extension but without bone marrow involvement

Yasuhiro Manabe, Yoshiyuki Hamakawa, Kazutaka Sunami, Yasuyuki Ohta, Nobuhiko Omori, Koji Abe

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

We report a very rare case of granulocytic sarcoma (GS) with muscle and peripheral nerve extension but without bone marrow involvement. A 53-year-old woman presented with sciatic pain and diplopia. Magnetic resonance imaging revealed bilateral orbital and cauda equina region tumors. The blood cell count, and bone marrow histology and cytology were normal. The characteristic cerebrospinal fluid (CSF) cytologic picture of CD14+, CD33+, CD4+, CD56+ and positive nonspecific erastase staining suggested the diagnosis of GS. The patient underwent intrathecal and systemic chemotherapy, as if she had acute myeloid leukemia (AML). This case emphasizes the value of CSF cytological examination and the use of an immunocytochemical marker.

Original languageEnglish
Pages (from-to)633-635
Number of pages3
JournalInternal Medicine
Volume46
Issue number9
DOIs
Publication statusPublished - May 1 2007

Fingerprint

Myeloid Sarcoma
Orbit
Peripheral Nerves
Cerebrospinal Fluid
Bone Marrow
Cauda Equina
Muscles
Diplopia
Blood Cell Count
Acute Myeloid Leukemia
Cell Biology
Histology
Magnetic Resonance Imaging
Staining and Labeling
Drug Therapy
Pain
Neoplasms

Keywords

  • Cerebrospinal fluid cytology
  • Granulocytic sarcoma
  • Meningeal extension

ASJC Scopus subject areas

  • Internal Medicine
  • Medicine(all)

Cite this

Granulocytic sarcoma with orbit, caude equina, muscle and peripheral nerve extension but without bone marrow involvement. / Manabe, Yasuhiro; Hamakawa, Yoshiyuki; Sunami, Kazutaka; Ohta, Yasuyuki; Omori, Nobuhiko; Abe, Koji.

In: Internal Medicine, Vol. 46, No. 9, 01.05.2007, p. 633-635.

Research output: Contribution to journalArticle

Manabe, Yasuhiro ; Hamakawa, Yoshiyuki ; Sunami, Kazutaka ; Ohta, Yasuyuki ; Omori, Nobuhiko ; Abe, Koji. / Granulocytic sarcoma with orbit, caude equina, muscle and peripheral nerve extension but without bone marrow involvement. In: Internal Medicine. 2007 ; Vol. 46, No. 9. pp. 633-635.
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