Granulocytic sarcoma of the intestine as a primary manifestation nine months prior to overt acute myelogenous leukemia

Hironobu Toki, Kenichi Okabe, Yoshiko Kimura, Katsuyuki Kiura, Hiroshi Shibata, Kyoko Hara, Shosuke Moriwaki, Takumi Nanbu, Akinori Iwashita

Research output: Contribution to journalArticlepeer-review

17 Citations (Scopus)

Abstract

A case of granulocytic sarcoma is reported. A 51-year-old male was found, upon laparotomy, to have a tumor mass in the terminal ileum. Nine months later, acute myelogenous leukemia (AML) was diagnosed upon a peripheral blood and bone marrow examination showing an increased number of abnormal myeloblasts. Scattered lesions of granulocytic sarcoma were found in the intestine, colon, testis, skin, gingiva and bone marrow. Chemotherapy, with multiple regimens for leukemia in combination, did not affect the tumor and the patient died 10 months following his development of overt leukemia. Detailed pathological findings are presented because of the difficulty in differentiating granulocytic sarcoma from non-Hodgkin's lymphoma.

Original languageEnglish
Pages (from-to)79-85
Number of pages7
JournalJapanese journal of clinical oncology
Volume17
Issue number1
Publication statusPublished - Mar 1987
Externally publishedYes

Keywords

  • Chloroma
  • Granulocytic sarcoma
  • Intestine
  • Leukemic change

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Cancer Research

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