Glioblastoma with metastasis to the spleen - Case report

Takao Yasuhara, Takashi Tamiya, Toshinari Meguro, Tomotsugu Ichikawa, Yumiko Sato, Isao Date, Hiroyuki Nakashima, Takashi Ohmoto

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

A 47-year-old woman presented with headache and left homonymous hemianopsia. T1-weighted magnetic resonance (MR) imaging with contrast medium showed a mass lesion with ring-like enhancement in the right temporo-occipital lobe. The patient underwent surgery, focal irradiation, and chemotherapy. The histological diagnosis was glioblastoma. Four months after the operation, the patient again developed headache and left homonymous hemianopsia in addition to vomiting and mild left hemiparesis. MR imaging showed recurrence of the tumor and hydrocephalus. The patient underwent a second craniotomy and placement of a ventriculoperitoneal shunt. Intraoperative findings revealed that the transverse-sigmoid sinus was occluded by tumor invasion. The patient died of intraventricular dissemination 2 months after the second operation. Autopsy revealed metastases in the spleen and lungs. Glioblastoma with metastases to the spleen is very rare. The prognosis for patients is poor. Excessive therapy should not be used for patients with extracranial metastases from glioblastoma.

Original languageEnglish
Pages (from-to)452-456
Number of pages5
JournalNeurologia Medico-Chirurgica
Volume43
Issue number9
DOIs
Publication statusPublished - Sep 1 2003

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Glioblastoma
Spleen
Neoplasm Metastasis
Hemianopsia
Headache
Magnetic Resonance Imaging
Transverse Sinuses
Ventriculoperitoneal Shunt
Occipital Lobe
Craniotomy
Sigmoid Colon
Paresis
Hydrocephalus
Contrast Media
Vomiting
Autopsy
Neoplasms
Recurrence
Drug Therapy
Lung

Keywords

  • Dural sinus occlusion
  • Glioblastoma
  • Spleen

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

Cite this

Glioblastoma with metastasis to the spleen - Case report. / Yasuhara, Takao; Tamiya, Takashi; Meguro, Toshinari; Ichikawa, Tomotsugu; Sato, Yumiko; Date, Isao; Nakashima, Hiroyuki; Ohmoto, Takashi.

In: Neurologia Medico-Chirurgica, Vol. 43, No. 9, 01.09.2003, p. 452-456.

Research output: Contribution to journalArticle

Yasuhara, T, Tamiya, T, Meguro, T, Ichikawa, T, Sato, Y, Date, I, Nakashima, H & Ohmoto, T 2003, 'Glioblastoma with metastasis to the spleen - Case report', Neurologia Medico-Chirurgica, vol. 43, no. 9, pp. 452-456. https://doi.org/10.2176/nmc.43.452
Yasuhara, Takao ; Tamiya, Takashi ; Meguro, Toshinari ; Ichikawa, Tomotsugu ; Sato, Yumiko ; Date, Isao ; Nakashima, Hiroyuki ; Ohmoto, Takashi. / Glioblastoma with metastasis to the spleen - Case report. In: Neurologia Medico-Chirurgica. 2003 ; Vol. 43, No. 9. pp. 452-456.
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