Genotoxicity analysis and hazardousness prioritization of a group of chemicals

E. Degirmenci, Y. Ono, O. Kawara, H. Utsumi

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Genotoxic chemicals are increasingly being used in our daily life. 180-chemicals were screened to identify the priority of hazardousness from the point of view of their genotoxicity. Umu-test was used to evaluate the genotoxicity of these chemicals. Some chemicals exhibited high genotoxic response. A scoring algorithm was developed to evaluate the hazardousness level of these chemicals based on their genotoxicity level and four other characteristics: biodegradation probability, soil adsorption coefficient (KOC), bioconcentration factor (BCF), Henry's Law constant (HLC). Then, these chemicals were sorted in a descending order of their hazardousness probability.

Original languageEnglish
Pages (from-to)125-131
Number of pages7
JournalWater Science and Technology
Volume42
Issue number7-8
Publication statusPublished - 2000

Fingerprint

genotoxicity
prioritization
Biodegradation
analysis
chemical
biodegradation
adsorption
Soils
Adsorption
soil

Keywords

  • BCF
  • Biodegradation probability
  • Genotoxicity
  • HLC
  • KOC
  • Umu-test

ASJC Scopus subject areas

  • Water Science and Technology

Cite this

Degirmenci, E., Ono, Y., Kawara, O., & Utsumi, H. (2000). Genotoxicity analysis and hazardousness prioritization of a group of chemicals. Water Science and Technology, 42(7-8), 125-131.

Genotoxicity analysis and hazardousness prioritization of a group of chemicals. / Degirmenci, E.; Ono, Y.; Kawara, O.; Utsumi, H.

In: Water Science and Technology, Vol. 42, No. 7-8, 2000, p. 125-131.

Research output: Contribution to journalArticle

Degirmenci, E, Ono, Y, Kawara, O & Utsumi, H 2000, 'Genotoxicity analysis and hazardousness prioritization of a group of chemicals', Water Science and Technology, vol. 42, no. 7-8, pp. 125-131.
Degirmenci, E. ; Ono, Y. ; Kawara, O. ; Utsumi, H. / Genotoxicity analysis and hazardousness prioritization of a group of chemicals. In: Water Science and Technology. 2000 ; Vol. 42, No. 7-8. pp. 125-131.
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