Genotoxicity analysis and hazardousness prioritization of a group of chemicals

E. Degirmenci, Y. Ono, O. Kawara, H. Utsumi

Research output: Contribution to journalConference article

5 Citations (Scopus)

Abstract

Genotoxic chemicals are increasingly being used in our daily life. 180-chemicals were screened to identify the priority of hazardousness from the point of view of their genotoxicity. Umu-test was used to evaluate the genotoxicity of these chemicals. Some chemicals exhibited high genotoxic response. A scoring algorithm was developed to evaluate the hazardousness level of these chemicals based on their genotoxicity level and four other characteristics: biodegradation probability, soil adsorption coefficient (KOC), bioconcentration factor (BCF), Henry's Law constant (HLC). Then, these chemicals were sorted in a descending order of their hazardousness probability.

Original languageEnglish
Pages (from-to)125-131
Number of pages7
JournalWater Science and Technology
Volume42
Issue number7-8
Publication statusPublished - Nov 27 2000
EventProceedings of the 3rd IAWQ Specialised Conference on Hazard Assessment and Control of Environmental Contaminants - Shiga, Jpn
Duration: Dec 5 1999Dec 8 1999

Keywords

  • BCF
  • Biodegradation probability
  • Genotoxicity
  • HLC
  • KOC
  • Umu-test

ASJC Scopus subject areas

  • Environmental Engineering
  • Water Science and Technology

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  • Cite this

    Degirmenci, E., Ono, Y., Kawara, O., & Utsumi, H. (2000). Genotoxicity analysis and hazardousness prioritization of a group of chemicals. Water Science and Technology, 42(7-8), 125-131.