Genetic modification of lignin biosynthesis for improved biofuel production

Hiroshi Hisano, Rangaraj Nandakumar, Zeng Yu Wang

Research output: Contribution to journalArticle

115 Citations (Scopus)

Abstract

The energy in cellulosic biomass largely resides in plant cell walls. Cellulosic biomass is more difficult than starch to break down into sugars because of the presence of lignin and the complex structure of cell walls. Transgenic down-regulation of major lignin genes led to reduced lignin content, increased dry matter degradability, and improved accessibility of cellulases for cellulose degradation. This review provides background information on lignin biosynthesis and focuses on genetic manipulation of lignin genes in important monocot species as well as the dicot potential biofuel crop alfalfa. Reduction of lignin in biofuel crops by genetic engineering is likely one of the most effective ways of reducing costs associated with pretreatment and hydrolysis of cellulosic feedstocks, although some potential fitness issues should also be addressed.

Original languageEnglish
Pages (from-to)306-313
Number of pages8
JournalIn Vitro Cellular and Developmental Biology - Animal
Volume45
Issue number3
DOIs
Publication statusPublished - Jun 2009
Externally publishedYes

Fingerprint

Biofuels
Lignin
biofuels
genetic engineering
lignin
biosynthesis
energy crops
Biomass
Cell Wall
cell walls
Cellulases
Genetic Engineering
cellulases
Medicago sativa
biomass
Plant Cells
Magnoliopsida
Liliopsida
feedstocks
dry matter content

Keywords

  • Biofuel crops
  • Biomass
  • Genetic engineering
  • Lignin modification

ASJC Scopus subject areas

  • Plant Science
  • Biotechnology

Cite this

Genetic modification of lignin biosynthesis for improved biofuel production. / Hisano, Hiroshi; Nandakumar, Rangaraj; Wang, Zeng Yu.

In: In Vitro Cellular and Developmental Biology - Animal, Vol. 45, No. 3, 06.2009, p. 306-313.

Research output: Contribution to journalArticle

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