Genetic basis of racemism and ease of interchiral mating in a clausiliid species of snails

Hiroki Utsuno, Shithila Kasem, Hiroshi Fukuda, Takahiro Asami

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Species that develop in left-right polarity reversal have repeatedly evolved in gastropods, uniquely among metazoans. To clarify mechanisms underlying the evolution of whole-body reversal, it is essential to understand the genetic variability of developmental polarity. Here we show experimental evidence for the maternal inheritance of racemism, in which both dextral and sinistral siblings are produced in the same broods, in the ovoviviparous land snail Hemizaptyx stimpsoni. In contrast to the traditionally known variation in left-right polarity that is determined by the dichotomous dextral and sinistral alleles, we found that a recessive allele at a nuclear locus is responsible for the present racemism. This genetic basis allowed us to estimate the frequency of the enantiomorphy allele to be 0.2 to 0.3 in the population where we found dextral variants. The ratio between dextral and sinistral siblings was close to 0.5 in total mean but bimodally distributed among maternal parents. The overall proportions of morphs changed across generations suggesting the operation of additional genetic factors. There was no detectable difference in the reproductive success of interchiral and intrachiral mating pairs. This suggests that positive frequency-dependent selection in high-spired snails may not necessarily be as strong as that known in the chirally-dimorphic Partula suturalis.

Original languageEnglish
Pages (from-to)37-47
Number of pages11
JournalMolluscan Research
Volume30
Issue number1
Publication statusPublished - 2010

Fingerprint

Snails
snail
snails
Ovoviviparity
allele
Alleles
alleles
Gastropoda
morphs
Gene Frequency
gene frequency
inheritance (genetics)
magnetic reversal
Mothers
gastropod
genetic variation
loci
reproductive success
Population
Maternal Inheritance

Keywords

  • Asymmetry
  • Enantiomorph
  • Frequency-dependent selection
  • Hemizaptyx stimpsoni
  • Maternal inheritance
  • Situs inversus

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Animal Science and Zoology
  • Genetics

Cite this

Genetic basis of racemism and ease of interchiral mating in a clausiliid species of snails. / Utsuno, Hiroki; Kasem, Shithila; Fukuda, Hiroshi; Asami, Takahiro.

In: Molluscan Research, Vol. 30, No. 1, 2010, p. 37-47.

Research output: Contribution to journalArticle

Utsuno, Hiroki ; Kasem, Shithila ; Fukuda, Hiroshi ; Asami, Takahiro. / Genetic basis of racemism and ease of interchiral mating in a clausiliid species of snails. In: Molluscan Research. 2010 ; Vol. 30, No. 1. pp. 37-47.
@article{d15f112856e5472c8b6b4a7ac6f58e98,
title = "Genetic basis of racemism and ease of interchiral mating in a clausiliid species of snails",
abstract = "Species that develop in left-right polarity reversal have repeatedly evolved in gastropods, uniquely among metazoans. To clarify mechanisms underlying the evolution of whole-body reversal, it is essential to understand the genetic variability of developmental polarity. Here we show experimental evidence for the maternal inheritance of racemism, in which both dextral and sinistral siblings are produced in the same broods, in the ovoviviparous land snail Hemizaptyx stimpsoni. In contrast to the traditionally known variation in left-right polarity that is determined by the dichotomous dextral and sinistral alleles, we found that a recessive allele at a nuclear locus is responsible for the present racemism. This genetic basis allowed us to estimate the frequency of the enantiomorphy allele to be 0.2 to 0.3 in the population where we found dextral variants. The ratio between dextral and sinistral siblings was close to 0.5 in total mean but bimodally distributed among maternal parents. The overall proportions of morphs changed across generations suggesting the operation of additional genetic factors. There was no detectable difference in the reproductive success of interchiral and intrachiral mating pairs. This suggests that positive frequency-dependent selection in high-spired snails may not necessarily be as strong as that known in the chirally-dimorphic Partula suturalis.",
keywords = "Asymmetry, Enantiomorph, Frequency-dependent selection, Hemizaptyx stimpsoni, Maternal inheritance, Situs inversus",
author = "Hiroki Utsuno and Shithila Kasem and Hiroshi Fukuda and Takahiro Asami",
year = "2010",
language = "English",
volume = "30",
pages = "37--47",
journal = "Molluscan Research",
issn = "1323-5818",
publisher = "Magnolia Press",
number = "1",

}

TY - JOUR

T1 - Genetic basis of racemism and ease of interchiral mating in a clausiliid species of snails

AU - Utsuno, Hiroki

AU - Kasem, Shithila

AU - Fukuda, Hiroshi

AU - Asami, Takahiro

PY - 2010

Y1 - 2010

N2 - Species that develop in left-right polarity reversal have repeatedly evolved in gastropods, uniquely among metazoans. To clarify mechanisms underlying the evolution of whole-body reversal, it is essential to understand the genetic variability of developmental polarity. Here we show experimental evidence for the maternal inheritance of racemism, in which both dextral and sinistral siblings are produced in the same broods, in the ovoviviparous land snail Hemizaptyx stimpsoni. In contrast to the traditionally known variation in left-right polarity that is determined by the dichotomous dextral and sinistral alleles, we found that a recessive allele at a nuclear locus is responsible for the present racemism. This genetic basis allowed us to estimate the frequency of the enantiomorphy allele to be 0.2 to 0.3 in the population where we found dextral variants. The ratio between dextral and sinistral siblings was close to 0.5 in total mean but bimodally distributed among maternal parents. The overall proportions of morphs changed across generations suggesting the operation of additional genetic factors. There was no detectable difference in the reproductive success of interchiral and intrachiral mating pairs. This suggests that positive frequency-dependent selection in high-spired snails may not necessarily be as strong as that known in the chirally-dimorphic Partula suturalis.

AB - Species that develop in left-right polarity reversal have repeatedly evolved in gastropods, uniquely among metazoans. To clarify mechanisms underlying the evolution of whole-body reversal, it is essential to understand the genetic variability of developmental polarity. Here we show experimental evidence for the maternal inheritance of racemism, in which both dextral and sinistral siblings are produced in the same broods, in the ovoviviparous land snail Hemizaptyx stimpsoni. In contrast to the traditionally known variation in left-right polarity that is determined by the dichotomous dextral and sinistral alleles, we found that a recessive allele at a nuclear locus is responsible for the present racemism. This genetic basis allowed us to estimate the frequency of the enantiomorphy allele to be 0.2 to 0.3 in the population where we found dextral variants. The ratio between dextral and sinistral siblings was close to 0.5 in total mean but bimodally distributed among maternal parents. The overall proportions of morphs changed across generations suggesting the operation of additional genetic factors. There was no detectable difference in the reproductive success of interchiral and intrachiral mating pairs. This suggests that positive frequency-dependent selection in high-spired snails may not necessarily be as strong as that known in the chirally-dimorphic Partula suturalis.

KW - Asymmetry

KW - Enantiomorph

KW - Frequency-dependent selection

KW - Hemizaptyx stimpsoni

KW - Maternal inheritance

KW - Situs inversus

UR - http://www.scopus.com/inward/record.url?scp=77958554955&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77958554955&partnerID=8YFLogxK

M3 - Article

VL - 30

SP - 37

EP - 47

JO - Molluscan Research

JF - Molluscan Research

SN - 1323-5818

IS - 1

ER -