An aldol-type reaction of boron aza-enolates with aldehydes is reported. N-Sulfonyl-1,2,3-triazoles react with pinacolborane in the presence of a nickel(0) catalyst to generate boron azaenolates with E geometry. The boron aza-enolates undergo an aldol-type reaction with aldehydes to give β-boroxy imines with syn configuration. The subsequent one-pot reduction with DIBALH gives 1,3-amino alcohols.
- Boron aza-enolates
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