Gene Expression Profiling and Differentiation of Immortalized Human Mesenchymal Stem Cells

Hiroki Mori, Junko Kato, Hirotami Matsuo, Tohru Nakanishi, Naoya Kobayashi, Yoshikazu Kosaka, Takashi Oka, Noriaki Tanaka

Research output: Contribution to journalArticlepeer-review

Abstract

Human bone marrow mesenchymal stem cells (hMSCs), tissue-derived stem cells, have the ability to differentiate into adipocytes, osteoblasts and chondrocytes, leading to attempt to apply these stem cells for regeneration of bone and cartilage. To address pluripotency of hMSCs, we analyzed gene expression profiles of several immortalized hMSCs with DNA chips that nearly covers the whole human genes. We isolated some factors that possibly relate to pluripotency of these hMSCs.

Original languageEnglish
Pages (from-to)267-268
Number of pages2
JournalJournal of Hard Tissue Biology
Volume14
Issue number2
DOIs
Publication statusPublished - Jan 2005

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Biochemistry
  • Biomaterials
  • Orthopedics and Sports Medicine
  • Dentistry(all)
  • Cell Biology

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