Gene expression of Jagged2 in mandibular condylar cartilage development

T. Shimizu; H. Tsujigiwa; H. Nagatsuka; K. Nakano; N. Okafuji; S. Kurihara; N. Nagai; Toshiyuki Kawakami

Gene expression of Jagged2 in mandibular condylar cartilage development

T. Shimizu, H. Tsujigiwa, H. Nagatsuka, K. Nakano, N. Okafuji, S. Kurihara, N. Nagai, Toshiyuki Kawakami

Research output: Contribution to journal › Article › peer-review

Abstract

Expression pattern of Jagged2 gene in mandibular condylar cartilage was examined by means of in situ hybridization (ISH) technique. At E14, Jagged2 mRNA signals appeared in cytoplasm of proliferating chondrocytes. From E15 to E19, Jagged2 mRNA was detected throughout almost all cytoplasm in all layers. However, the distribution pattern was not uniform. These results suggest that Jagged2 plays an essential role for mandibular condylar cartilage morphogenesis and development.

Original language	English
Pages (from-to)	1-3
Number of pages	3
Journal	European journal of medical research
Volume	13
Issue number	1
Publication status	Published - Jan 23 2008
Externally published	Yes

Keywords

In situ hybridization
Jagged2 gene
Mandibular condylar cartilage
Secondary cartilage

ASJC Scopus subject areas

Medicine(all)

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abstract = "Expression pattern of Jagged2 gene in mandibular condylar cartilage was examined by means of in situ hybridization (ISH) technique. At E14, Jagged2 mRNA signals appeared in cytoplasm of proliferating chondrocytes. From E15 to E19, Jagged2 mRNA was detected throughout almost all cytoplasm in all layers. However, the distribution pattern was not uniform. These results suggest that Jagged2 plays an essential role for mandibular condylar cartilage morphogenesis and development.",

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AU - Shimizu, T.

AU - Tsujigiwa, H.

AU - Nagatsuka, H.

AU - Nakano, K.

AU - Okafuji, N.

AU - Kurihara, S.

AU - Nagai, N.

AU - Kawakami, Toshiyuki

PY - 2008/1/23

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N2 - Expression pattern of Jagged2 gene in mandibular condylar cartilage was examined by means of in situ hybridization (ISH) technique. At E14, Jagged2 mRNA signals appeared in cytoplasm of proliferating chondrocytes. From E15 to E19, Jagged2 mRNA was detected throughout almost all cytoplasm in all layers. However, the distribution pattern was not uniform. These results suggest that Jagged2 plays an essential role for mandibular condylar cartilage morphogenesis and development.

AB - Expression pattern of Jagged2 gene in mandibular condylar cartilage was examined by means of in situ hybridization (ISH) technique. At E14, Jagged2 mRNA signals appeared in cytoplasm of proliferating chondrocytes. From E15 to E19, Jagged2 mRNA was detected throughout almost all cytoplasm in all layers. However, the distribution pattern was not uniform. These results suggest that Jagged2 plays an essential role for mandibular condylar cartilage morphogenesis and development.

KW - In situ hybridization

KW - Jagged2 gene

KW - Mandibular condylar cartilage

KW - Secondary cartilage

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