Abstract
Expression pattern of Jagged2 gene in mandibular condylar cartilage was examined by means of in situ hybridization (ISH) technique. At E14, Jagged2 mRNA signals appeared in cytoplasm of proliferating chondrocytes. From E15 to E19, Jagged2 mRNA was detected throughout almost all cytoplasm in all layers. However, the distribution pattern was not uniform. These results suggest that Jagged2 plays an essential role for mandibular condylar cartilage morphogenesis and development.
| Original language | English |
|---|---|
| Pages (from-to) | 1-3 |
| Number of pages | 3 |
| Journal | European journal of medical research |
| Volume | 13 |
| Issue number | 1 |
| Publication status | Published - Jan 23 2008 |
| Externally published | Yes |
Keywords
- In situ hybridization
- Jagged2 gene
- Mandibular condylar cartilage
- Secondary cartilage
ASJC Scopus subject areas
- Medicine(all)
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Cite this
Shimizu, T., Tsujigiwa, H., Nagatsuka, H., Nakano, K., Okafuji, N., Kurihara, S., Nagai, N., & Kawakami, T. (2008). Gene expression of Jagged2 in mandibular condylar cartilage development. European journal of medical research, 13(1), 1-3.