Gastric mucosal injury induced by chloral hydrate

Ogino Keiki, Hobara Tatuya, Kobayashi Haruo, Iwamoto Susumu

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)

Abstract

Gastric mucosal injury by chloral hydrate (CH) was investigated in the rat. Rats were injected with CH intraperitoneally or subcutaneously. After the CH injection, gastric ulcers appeared in the glandular stomach at 6 h and the ulcer index peaked in 12 h. The minimum dosage of CH to produce ulcers was 400 mg/ kg intraperitoneally and 600 mg/kg subcutaneously.

Original languageEnglish
Pages (from-to)129-133
Number of pages5
JournalToxicology Letters
Volume52
Issue number2
DOIs
Publication statusPublished - Jul 1990

Keywords

  • Chloral hydrate
  • Stomach
  • Ulcer

ASJC Scopus subject areas

  • Toxicology

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