Gastric bezoar treatment by endoscopic fragmentation in combination with Pepsi-Cola® administration

Masaya Iwamuro, Naoko Yunoki, Jun Tomoda, Kazuhiro Nakamura, Hiroyuki Okada, Kazuhide Yamamoto

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)


Objective: Unusual setting of medical care Background: Although bezoar dissolution by Coca-Cola® has been described in case reports and case series, to the best of our knowledge, the usefulness of other cola products such as Pepsi-Cola® has never been reported in the English literature. Case Report: An 86-year-old Taiwanese man was diagnosed with a gastric bezoar. Endoscopic fragmentation with a polypectomy snare was attempted twice but failed to remove the bezoar. Subsequently, 500 mL of Pepsi NEX Zero® was administered daily for 4 days via nasogastric tube. The bezoar was softened and successfully fragmented by the polypectomy snare and needle-knife devices on the third attempt. Conclusions: This report presents the first case of a gastric bezoar successfully treated by endoscopic fragmentation in combination with Pepsi-Cola® administration, suggesting the possible utility of cola beverages in bezoar treatment, regardless of product brands.

Original languageEnglish
Pages (from-to)445-448
Number of pages4
JournalAmerican Journal of Case Reports
Publication statusPublished - Jul 10 2015
Externally publishedYes


  • Bezoars
  • Cola
  • Endoscopy
  • Foreign bodies
  • Gastrointestinal

ASJC Scopus subject areas

  • Medicine(all)

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