Functional monomer impurity affects adhesive performance

Kumiko Yoshihara, Noriyuki Nagaoka, Takumi Okihara, Manabu Kuroboshi, Satoshi Hayakawa, Yukinori Maruo, Goro Nishigawa, Jan De Munck, Yasuhiro Yoshida, Bart Van Meerbeek

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Objective The functional monomer 10-MDP has been considered as one of the best performing functional monomers for dental adhesives. Different adhesives containing 10-MDP are commercially available, among which many so-called 'universal' adhesives. We hypothesize that the quality of the functional monomer 10-MDP in terms of purity may affect bonding performance. Methods We therefore characterized three different 10-MDP versions (10-MDP-KN provided by Kuraray Noritake; 10-MDP-PCM provided by PCM; 10-MDP-DMI provided by DMI) using NMR, and analyzed their ability to form 10-MDP-Ca salts on dentin using XRD. The 'immediate' and 'aged' micro-tensile bond strength (μTBS) to dentin of three experimental 10-MDP primers was measured. The resultant interfacial adhesive-dentin ultra-structure was characterized using TEM. Results NMR disclosed impurities and the presence of 10-MDP dimer in 10-MDP-PCM and 10-MDP-DMI. 10-MDP-PCM and 10-MDP-DMI appeared also sensitive to hydrolysis. 10-MDP-KN, on the contrary, contained less impurities and dimer, and did not undergo hydrolysis. XRD revealed more intense 10-MDP-Ca salt deposition on dentin induced by 10-MDP-KN. The adhesive based on the experimental 10-MDP-KN primer resulted in a significantly higher 'immediate' bond strength that remained stable upon aging; the μTBS of the experimental 10-MDP-PCM and 10-MDP-DMI adhesives significantly dropped upon aging. TEM revealed thicker hybridization and more intense nano-layering for 10-MDP-KN. Significance It was concluded that primer impurities and the presence of 10-MDP dimer affected not only hybridization, but also reduced the formation of 10-MDP-Ca salts and nano-layering. 10-MDP in a high purity grade is essential to achieve durable bonding.

Original languageEnglish
Pages (from-to)1493-1501
Number of pages9
JournalDental Materials
Volume31
Issue number12
DOIs
Publication statusPublished - Dec 1 2015

Fingerprint

Pulse code modulation
Adhesives
Dentin
Monomers
Impurities
Dimers
Salts
Tensile Strength
Hydrolysis
Aging of materials
Nuclear magnetic resonance
Dental Cements
Transmission electron microscopy

Keywords

  • Adhesion
  • Dentin
  • Functional monomer
  • Impurity
  • NMR
  • TEM

ASJC Scopus subject areas

  • Dentistry(all)
  • Materials Science(all)
  • Mechanics of Materials

Cite this

Functional monomer impurity affects adhesive performance. / Yoshihara, Kumiko; Nagaoka, Noriyuki; Okihara, Takumi; Kuroboshi, Manabu; Hayakawa, Satoshi; Maruo, Yukinori; Nishigawa, Goro; De Munck, Jan; Yoshida, Yasuhiro; Van Meerbeek, Bart.

In: Dental Materials, Vol. 31, No. 12, 01.12.2015, p. 1493-1501.

Research output: Contribution to journalArticle

Yoshihara, Kumiko ; Nagaoka, Noriyuki ; Okihara, Takumi ; Kuroboshi, Manabu ; Hayakawa, Satoshi ; Maruo, Yukinori ; Nishigawa, Goro ; De Munck, Jan ; Yoshida, Yasuhiro ; Van Meerbeek, Bart. / Functional monomer impurity affects adhesive performance. In: Dental Materials. 2015 ; Vol. 31, No. 12. pp. 1493-1501.
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AU - Yoshihara, Kumiko

AU - Nagaoka, Noriyuki

AU - Okihara, Takumi

AU - Kuroboshi, Manabu

AU - Hayakawa, Satoshi

AU - Maruo, Yukinori

AU - Nishigawa, Goro

AU - De Munck, Jan

AU - Yoshida, Yasuhiro

AU - Van Meerbeek, Bart

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N2 - Objective The functional monomer 10-MDP has been considered as one of the best performing functional monomers for dental adhesives. Different adhesives containing 10-MDP are commercially available, among which many so-called 'universal' adhesives. We hypothesize that the quality of the functional monomer 10-MDP in terms of purity may affect bonding performance. Methods We therefore characterized three different 10-MDP versions (10-MDP-KN provided by Kuraray Noritake; 10-MDP-PCM provided by PCM; 10-MDP-DMI provided by DMI) using NMR, and analyzed their ability to form 10-MDP-Ca salts on dentin using XRD. The 'immediate' and 'aged' micro-tensile bond strength (μTBS) to dentin of three experimental 10-MDP primers was measured. The resultant interfacial adhesive-dentin ultra-structure was characterized using TEM. Results NMR disclosed impurities and the presence of 10-MDP dimer in 10-MDP-PCM and 10-MDP-DMI. 10-MDP-PCM and 10-MDP-DMI appeared also sensitive to hydrolysis. 10-MDP-KN, on the contrary, contained less impurities and dimer, and did not undergo hydrolysis. XRD revealed more intense 10-MDP-Ca salt deposition on dentin induced by 10-MDP-KN. The adhesive based on the experimental 10-MDP-KN primer resulted in a significantly higher 'immediate' bond strength that remained stable upon aging; the μTBS of the experimental 10-MDP-PCM and 10-MDP-DMI adhesives significantly dropped upon aging. TEM revealed thicker hybridization and more intense nano-layering for 10-MDP-KN. Significance It was concluded that primer impurities and the presence of 10-MDP dimer affected not only hybridization, but also reduced the formation of 10-MDP-Ca salts and nano-layering. 10-MDP in a high purity grade is essential to achieve durable bonding.

AB - Objective The functional monomer 10-MDP has been considered as one of the best performing functional monomers for dental adhesives. Different adhesives containing 10-MDP are commercially available, among which many so-called 'universal' adhesives. We hypothesize that the quality of the functional monomer 10-MDP in terms of purity may affect bonding performance. Methods We therefore characterized three different 10-MDP versions (10-MDP-KN provided by Kuraray Noritake; 10-MDP-PCM provided by PCM; 10-MDP-DMI provided by DMI) using NMR, and analyzed their ability to form 10-MDP-Ca salts on dentin using XRD. The 'immediate' and 'aged' micro-tensile bond strength (μTBS) to dentin of three experimental 10-MDP primers was measured. The resultant interfacial adhesive-dentin ultra-structure was characterized using TEM. Results NMR disclosed impurities and the presence of 10-MDP dimer in 10-MDP-PCM and 10-MDP-DMI. 10-MDP-PCM and 10-MDP-DMI appeared also sensitive to hydrolysis. 10-MDP-KN, on the contrary, contained less impurities and dimer, and did not undergo hydrolysis. XRD revealed more intense 10-MDP-Ca salt deposition on dentin induced by 10-MDP-KN. The adhesive based on the experimental 10-MDP-KN primer resulted in a significantly higher 'immediate' bond strength that remained stable upon aging; the μTBS of the experimental 10-MDP-PCM and 10-MDP-DMI adhesives significantly dropped upon aging. TEM revealed thicker hybridization and more intense nano-layering for 10-MDP-KN. Significance It was concluded that primer impurities and the presence of 10-MDP dimer affected not only hybridization, but also reduced the formation of 10-MDP-Ca salts and nano-layering. 10-MDP in a high purity grade is essential to achieve durable bonding.

KW - Adhesion

KW - Dentin

KW - Functional monomer

KW - Impurity

KW - NMR

KW - TEM

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