Fulminant hepatitis: Who survives without liver transplantation?

Yasuhiro Miyake, Tetsuya Yasunaka, Fusao Ikeda, Akinobu Takaki, Kazuhiro Nouso, Kazuhide Yamamoto

Research output: Contribution to journalArticle

Abstract

Aim: In order to rescue more patients with fulminant hepatitis (FH) in a setting of the shortage of liver grafts, it is important not only to determine the suitable timing for liver transplantation (LT) but also to reduce avoidable operations for patients surviving without LT. This study aimed to identify prognostic parameters for survival without LT in FH patients. Methods: In 96 FH patients who did not receive LT, we examined prognostic parameters at the time of the diagnosis of FH, which were associated with patient's survival. Results: Fifty-three patients (55%) were female. The median age was 48years. At the time of the diagnosis of FH, hepatic coma grade was II in 63 patients (66%), III in 22 (23%) and IV in 11 (11%). Forty-six patients (48%) were in a state of systemic inflammatory response syndrome (SIRS). Four parameters of age (0.65), and total bilirubin (

Original languageEnglish
Pages (from-to)60-67
Number of pages8
JournalHepatology Research
Volume42
Issue number1
DOIs
Publication statusPublished - Jan 2012

Fingerprint

Liver Transplantation
Hepatitis
Systemic Inflammatory Response Syndrome
Survival
Hepatic Encephalopathy
Bilirubin
Transplants
Liver

Keywords

  • Fulminant hepatitis
  • Liver transplantation
  • Prognostic factor
  • Survival
  • Systemic inflammatory response syndrome

ASJC Scopus subject areas

  • Hepatology
  • Infectious Diseases

Cite this

Fulminant hepatitis : Who survives without liver transplantation? / Miyake, Yasuhiro; Yasunaka, Tetsuya; Ikeda, Fusao; Takaki, Akinobu; Nouso, Kazuhiro; Yamamoto, Kazuhide.

In: Hepatology Research, Vol. 42, No. 1, 01.2012, p. 60-67.

Research output: Contribution to journalArticle

Miyake, Yasuhiro ; Yasunaka, Tetsuya ; Ikeda, Fusao ; Takaki, Akinobu ; Nouso, Kazuhiro ; Yamamoto, Kazuhide. / Fulminant hepatitis : Who survives without liver transplantation?. In: Hepatology Research. 2012 ; Vol. 42, No. 1. pp. 60-67.
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