TY - JOUR
T1 - Fractionation of pharmacologically active plant polyphenols by centrifugal partition chromatography
AU - Okuda, Takuo
AU - Yoshida, Takashi
AU - Hatano, Tsutomu
AU - Mori, Kazuko
AU - Fukuda, Toshiyuki
PY - 1990/11/1
Y1 - 1990/11/1
N2 - Centrifugal partition chromatography (CPC) has been applied to the preparative fractionation of pharmacologically active polyphenols contained in the crude extracts from three medicinal plants. 1) (-)-Epigallocatechin gallate, the main component of tea polyphenols, which inhibits tumor promotion, 2) oligomeric hydrolyzable tannins, having host-mediated anti-tumor activity and antiviral activity, contained in Woodfordia fruticosa flower, 3) polyphenolic components of licorice, having anti-HIV activity. The results obtained with cartridges of medium volume and of small volume were compared during the fractionation of tea polyphenols.
AB - Centrifugal partition chromatography (CPC) has been applied to the preparative fractionation of pharmacologically active polyphenols contained in the crude extracts from three medicinal plants. 1) (-)-Epigallocatechin gallate, the main component of tea polyphenols, which inhibits tumor promotion, 2) oligomeric hydrolyzable tannins, having host-mediated anti-tumor activity and antiviral activity, contained in Woodfordia fruticosa flower, 3) polyphenolic components of licorice, having anti-HIV activity. The results obtained with cartridges of medium volume and of small volume were compared during the fractionation of tea polyphenols.
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U2 - 10.1080/01483919008049561
DO - 10.1080/01483919008049561
M3 - Article
AN - SCOPUS:0025650280
SN - 1082-6076
VL - 13
SP - 3637
EP - 3650
JO - Journal of Liquid Chromatography and Related Technologies
JF - Journal of Liquid Chromatography and Related Technologies
IS - 18
ER -
