Fournier's gangrene after unrelated cord blood stem cell transplantation

C. Yoshida, K. Kojima, K. Shinagawa, D. Hashimoto, S. Asakura, S. Takata, M. Tanimoto

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)

Abstract

A 16-year-old boy with refractory acute myelogenous leukemia developed Fournier's gangrene as an early complication after two-antigen HLA-mismatched unrelated cord blood stem cell transplantation. On day 25 after the transplantation, he noted abrupt onset of penile swelling with miction pain. The penile inflammation rapidly extended posteriorly to involve the scrotum and perianal tissues, inferiorly to involve the thighs, and superiorly up the lower abdominal region within the next 36 h, and he died from sepsis on day 27. Fournier's gangrene presenting as a genitoperineal necrotizing fasciitis should be considered as a potential complication in umbilical-cord blood recipients in the cytopenic post-transplant phase.

Original languageEnglish
Pages (from-to)538-539
Number of pages2
JournalAnnals of Hematology
Volume81
Issue number9
DOIs
Publication statusPublished - Dec 1 2002

Keywords

  • Acute myelogenous leukemia
  • Cord blood stem cell tranplantation
  • Fournier's gangrene
  • Necrotizing fasciitis

ASJC Scopus subject areas

  • Hematology

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