Formation of periodic nanostructures using a femtosecond laser to control cell spreading on titanium

Togo Shinonaga, M. Tsukamoto, T. Kawa, P. Chen, A. Nagai, T. Hanawa

Research output: Contribution to journalArticle

26 Citations (Scopus)


Although titanium (Ti) is a common biomaterial, controlling cell spreading by forming periodic structures using a femtosecond laser should improve its biocompatibility. Herein we investigate the influence of periodic nanostructures formed on the surface of a Ti plate on cell spreading. Nanostructures with a periodicity of 590 nm are formed using a femtosecond laser with a wavelength of 775 nm. Cell spreading on the plate without period structures lacks a definite direction, whereas cell spreading on the Ti plate with periodic structures occurs along the grooves, suggesting that forming periodic structures via a femtosecond laser can control cell spreading.

Original languageEnglish
Pages (from-to)493-496
Number of pages4
JournalApplied Physics B: Lasers and Optics
Publication statusPublished - 2015
Externally publishedYes


ASJC Scopus subject areas

  • Physics and Astronomy(all)
  • Physics and Astronomy (miscellaneous)

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