Abstract
The microphase separation of lipid molecules on a vesicle membrane can be induced, depending on the difference in the geometric structures of their headgroups. Through cryo-transmission-electron-microscopy analysis, a lens-like vesicle was prepared by mixing 50 wt% Span 40 (sorbitan monopalmitate) and 50 wt% Tween 40 [polyoxyethylene (20) sorbitan monopalmitate]. Considering the molecular structures of Span 40 and Tween 40, the high-curvature region was mainly formed by Tween 40. As determined by Fourier-transform infrared spectroscopy, dielectric-dispersion analysis, and differential scanning calorimetry, a hydration layer was likely formed because polyoxyethylene conjugates with the headgroups of Tween 40. These investigations of the obtained self-assembled aggregates of nonionic surfactants with heterogeneous surfaces could contribute to the development of new types of biomaterials.
| Original language | English |
|---|---|
| Pages (from-to) | 235-242 |
| Number of pages | 8 |
| Journal | Colloids and Surfaces B: Biointerfaces |
| Volume | 135 |
| DOIs | |
| Publication status | Published - Nov 1 2015 |
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Keywords
- Nonionic-surfactant vesicle
- Phase separation
- Self-assembled aggregate
ASJC Scopus subject areas
- Biotechnology
- Colloid and Surface Chemistry
- Physical and Theoretical Chemistry
- Surfaces and Interfaces
Cite this
Formation of lens-like vesicles induced via microphase separations on a sorbitan monoester membrane with different headgroups. / Hayashi, Keita; Iwai, Hideka; Shimanouchi, Toshinori; Umakoshi, Hiroshi; Iwasaki, Tomoyuki; Kato, Ayako; Nakamura, Hidemi.
In: Colloids and Surfaces B: Biointerfaces, Vol. 135, 01.11.2015, p. 235-242.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Formation of lens-like vesicles induced via microphase separations on a sorbitan monoester membrane with different headgroups
AU - Hayashi, Keita
AU - Iwai, Hideka
AU - Shimanouchi, Toshinori
AU - Umakoshi, Hiroshi
AU - Iwasaki, Tomoyuki
AU - Kato, Ayako
AU - Nakamura, Hidemi
PY - 2015/11/1
Y1 - 2015/11/1
N2 - The microphase separation of lipid molecules on a vesicle membrane can be induced, depending on the difference in the geometric structures of their headgroups. Through cryo-transmission-electron-microscopy analysis, a lens-like vesicle was prepared by mixing 50 wt% Span 40 (sorbitan monopalmitate) and 50 wt% Tween 40 [polyoxyethylene (20) sorbitan monopalmitate]. Considering the molecular structures of Span 40 and Tween 40, the high-curvature region was mainly formed by Tween 40. As determined by Fourier-transform infrared spectroscopy, dielectric-dispersion analysis, and differential scanning calorimetry, a hydration layer was likely formed because polyoxyethylene conjugates with the headgroups of Tween 40. These investigations of the obtained self-assembled aggregates of nonionic surfactants with heterogeneous surfaces could contribute to the development of new types of biomaterials.
AB - The microphase separation of lipid molecules on a vesicle membrane can be induced, depending on the difference in the geometric structures of their headgroups. Through cryo-transmission-electron-microscopy analysis, a lens-like vesicle was prepared by mixing 50 wt% Span 40 (sorbitan monopalmitate) and 50 wt% Tween 40 [polyoxyethylene (20) sorbitan monopalmitate]. Considering the molecular structures of Span 40 and Tween 40, the high-curvature region was mainly formed by Tween 40. As determined by Fourier-transform infrared spectroscopy, dielectric-dispersion analysis, and differential scanning calorimetry, a hydration layer was likely formed because polyoxyethylene conjugates with the headgroups of Tween 40. These investigations of the obtained self-assembled aggregates of nonionic surfactants with heterogeneous surfaces could contribute to the development of new types of biomaterials.
KW - Nonionic-surfactant vesicle
KW - Phase separation
KW - Self-assembled aggregate
UR - http://www.scopus.com/inward/record.url?scp=84938767645&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84938767645&partnerID=8YFLogxK
U2 - 10.1016/j.colsurfb.2015.07.071
DO - 10.1016/j.colsurfb.2015.07.071
M3 - Article
VL - 135
SP - 235
EP - 242
JO - Colloids and Surfaces B: Biointerfaces
JF - Colloids and Surfaces B: Biointerfaces
SN - 0927-7765
ER -