Formal hydrochromination of alkynes under nickel catalysis. Regioselective reductive coupling of alkynes and aldehydes leading to allylic alcohols

Kazuhiko Takai, Shuji Sakamoto, Takahiko Isshiki, Tatsuya Kokumai

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Formal hydrochromation of an alkyne leading to a 1-substituted ethenylchromium reagent is accomplished by addition of the alkyne and water to a mixture of low-valent chromium(II), a catalytic amount of nickel(II), and triphenylphosphine in DMF.

Original languageEnglish
Pages (from-to)7534-7539
Number of pages6
JournalTetrahedron
Volume62
Issue number32
DOIs
Publication statusPublished - Aug 7 2006

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Fingerprint Dive into the research topics of 'Formal hydrochromination of alkynes under nickel catalysis. Regioselective reductive coupling of alkynes and aldehydes leading to allylic alcohols'. Together they form a unique fingerprint.

  • Cite this